Prof. Dr.Banu Kumbak Aygün

  • İlgi Alanları
  • Kısırlık
  • Tüp bebek
  • Endoskopik cerrahiler
  • Polikistik over sendromu
  • Endometriozis cerrahisi

Eğitim ve Uzmanlık
Hacettepe Üniversitesi Tıp Fakultesi (ing), Tıp Doktoru, 1996 
İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Kadın Hastalıkları ve Doğum AD, Kadın Hastalıkları ve Doğum Uzmanı, 2001
Yardımla Üreme Tedavileri Uzmanı, 2005
Kadın Hastalıkları ve Doğum Doçenti, 2011
Kadın Hastalıkları ve Doğum Profesörü, 2017
İAU VM Medical Park Hastanesi Kadın Hastalıkları ve Doğum Anabilim Dalı

İstanbul Memorial Hastanesi Tüp Bebek ve Genetik Merkezi
Bahçeci Umut Tüp Bebek Merkezi
Fırat Üniversitesi Kadın Hastalıkları ve Doğum AD, Tüp Bebek Merkezi Sorumlu Öğretim Üyesi
Medipol Üniversitesi Kadın Hastalıkları ve Doğum AD, Tüp Bebek Merkezi Kurucu ve Sorumlu Öğretim Üyesi
Acıbadem Taksim Hastanesi Kadın Hastalıkları ve Doğum Uzmanı  


 Uluslararası hakemli dergilerde yayımlanan makaleler:
A1. N. Ilhan, BK. Aygun, H. Gungor., ‘’ The relationship between the latency period, infection markers, and oxidant and antioxidant states in women with preterm premature rupture of membranes.’’, Ir J Med Sci 2017;Feb 6. doi: 10.1007/s11845-017-1570-7. 
A2. O. Celik, N. Celik, S. Aydin, BK. Aygun, ET. Haberal, T. Kuloglu, M. Ulas, LH. Aktun, M. Acet, S. Celik., ‘’ Ghrelin action on GnRH neurons and pituitary gonadotropes might be mediated by GnIH-GPR147 system.’’,  Horm Mol Biol Clin Investig 2016;25:121-8. doi: 10.1515/hmbci-2015-0050. Review.
A3. O. Celik, BK. Aygun, N. Celik, S. Aydin, ET. Haberal, L. Sahin, Y. Yavuz, S. Celik., ‘’ Great migration: epigenetic reprogramming and germ cell-oocyte metamorphosis determine individual ovarian reserve.’’, Horm Mol Biol Clin Investig 2016;25:45-63. doi: 10.1515/hmbci-2015-0049. Review.
A4. HL. Aktun, B. Yorgunlar, M. Acet, BK. Aygun, N. Karaca., ‘’ The effects of polycystic ovary syndrome on gestational diabetes mellitus.’’, Gynecol Endocrinol 2016;32:139-42. doi: 10.3109/09513590.2015.1101438. 
A5. B. Kumbak, L. Sahin, S. Ozkan, R. Atilgan., ‘’Response to: Impact of luteal phase hysteroscopy and concurrent endometrial biopsy on subsequent IVF cycle outcome’’, Arch Gynecol Obstet 2015;291:479-80. doi: 10.1007/s00404-014-3584-y.
A6. R. Atilgan, T.Kuloglu, ZS. Ozkan, SB. Kavak, B.Kumbak, D. Deveci, M.Simsek, M.Baspinar, E. Sapmaz., ‘’Evaluation of vitamin C and vitamin E for prevention of postoperative adhesion: A rat uterine horn model study’’, J Obstet Gynecol Res 2015;41:418-23.  doi: 10.1111/jog.12544.
A7. N. İlhan, E. Celik, B. Kumbak., ‘’ Maternal plasma levels of IL-6, CRP, vitamins C, E and A, 8-isoprostane and oxidative status in women with preterm premature rupture of membranes’’, J Matern Fetal Neonatal Med 2015;28:316-9. doi: 10.3109/14767058.2014.916674.
A8. B. Kumbak, L.Sahin, S.Ozkan, R.Atilgan., ‘’Impact of luteal phase hysteroscopy and concurrent endometrial biopsy on subsequent IVF cycle outcome’’, Arch Gynecol Obstet 2014;290:369-74. doi: 10.1007/s00404-014-3211-y.
A9. ZS. Ozkan, D. Deveci, B. Kumbak, M. Simsek, F. Ilhan, S. Sekercioglu, E. Sapmaz., ‘’What is the impact of Th1/Th2 ratio, SOCS3, IL17, and IL35 levels in unexplained infetility?’’, J Reprod Immunol 2014;103:53-8. doi: 10.1016/j.jri.2013.11.002.
A10. B. Kumbak, AK. Poyraz, M. Baspinar, L. Sahin, ZS. Ozkan., ‘’Lower extremity venous Doppler evaluation in patients undergoing laparoscopic gynecological operations’’, J Laparoendosc Adv Surg Tech A 2013;23:926-31. doi: 10.1089/lap.2012.0487.    
A11. O. Celik, E. Celik, E. Yilmaz, N. Celik, I. Turkcuoglu, M. Ulas, B. Kumbak, E. Aktan, I. Ozerol., ‘’Effect of ovarian stimulation with recombinant follicle-stimulating hormone, gonadotropin-releasing hormone agonist and antagonists, on follicular fluid stem cell factor and serum urocortin 1 levels on the day of oocyte retrieval’’, Arch Gynecol Obstet 2013;288:1417-22. doi: 10.1007/s00404-013-2804-1.  
A12. B. Kumbak, E. Oral, O. Bukulmez., ‘’Female obesity and assisted reproductive technologies’’, Semin Reprod Med 2012;30:507-16. doi: 10.1055/s-0032-1328879.
A13. L. Sahin, B. Kumbak Aygun., ‘’Normal pregnancy outcome in a woman with chronic myeloid leukemia and epilepsy: a case report and review of the literature’, Case Rep Perinat Med 2012; isssue 1(1-2): 47-50.
A14. B. Kumbak Aygun, G. Goktolga Pinar, L. Sahin, ZS. Ozkan, AK. Poyraz, C. Aygun., ‘’Budd- Chiari Syndrome following vaginal delivery in a patient with Crohn’s Disease. A case report and review of the literature’’, Case Rep Perinat Med 2013; Issue 1-2; pp 17-21.
A15. E. Celik, O. Celik, B. Kumbak, E. Yilmaz, I. Turkcuoglu, Y. Simsek, A. Karaer, Y. Minareci, E. Ozerol, K. Tanbek., ‘’A comparative study on oxidative and antioxidative markers of serum and follicular fluid in GnRH agonist and antagonist cycles’’, J Assist Reprod Genet 2012;29:1175-83. doi: 10.1007/s10815-012-9843-6. 
A16. C.F. Demir, M. Yildiz, H. Ozdemir, O. Kapan, Z. Bozgeyik, S. Berilgen, B. Aygun, F.S. Erol., ‘’Paraplegia in pregnancy: a case report of spinal vascular malformation with Klippel-Trenaunay Syndrome’’, Spine 2012;37:E1218-20.  doi: 10.1097/BRS.0b013e31825c66ab.
A17. S. Kavvasoglu, Z.S. Ozkan, B. Kumbak, M. Sımsek, N. Ilhan., ‘’Association of kisspeptin-10 levels with abortus imminens: a preliminary study’’, Arch Gynecol Obstet 2012;285: 649-53. doi: 10.1007/s00404-011-2061-0.
A18. Z.S. Ozkan, B. Kumbak, H. Cilgin, M. Simsek, B. Aydin Turk., ‘’Coexistence of adenomyosis in women operated for benign gynecological diseases’’, Gynecol Endocrinol 2012;28: 212-5. doi: 10.3109/09513590.2011.593669. 
A19. E. Coskun, Y. Cakiroglu, B.K. Aygun, B. Muezzinoglu, E. Caliskan., ‘’Effect of copper intrauterine device on the cyclooxygenase and inducible nitric oxide synthase expression in the luteal phase endometrium’’, Contraception 2011;84:637-41. doi: 10.1016/j.contraception.2011.03.027. 
A20. Z.S. Ozkan, B. Kumbak, E. Sapmaz, M. Simsek., ‘’Myometrial cystic formation after local methotrexate application into cornual gestational sac: a case report of an unexpected complication’’, Case Rep Obstet Gynecol 2011;2011: 619094. doi: 10.1155/2011/619094. 
A21. Z.S. Ozkan, H. Cilgin, H.B. Aygün, D. Deveci, M. Simşek, S. Kumru, H. Yüce., ‘’Our clinical experience about prenatal diagnosis and neonatal outcomes of fetal central nervous system anomalies’’, J Matern Fetal Neonatal Med 2011;24: 502-5. doi: 10.3109/14767058.2010.501125. 
A22. B. Kumbak, Z.S. Ozkan, M. Simsek., ‘’Heterotopic pregnancy following bilateral tubal ligation: Case report’’, Eur J Contracept Reprod Health Care 2011;16: 319-21. doi: 10.3109/13625187.2011.577541.
A23. R. Attar, G. Yildirim, B. Kumbak, C. Ficicioglu, S. Demirbag, N. Yesildaglar., ‘’Efficacy of melatonin and hyaluronate/carboxymethylcellulose membrane in preventing adhesion re-formation following adhesiolysis in the rat uterine mode’’,  J Obstet Gynaecol Res 2011;37: 125-31. doi: 10.1111/j.1447-0756.2010.01329.x.
A24. B. Kumbak, H. Celik, B. Cobanoglu, B. Gurates., ‘’Paratubal borderline tumor incidentally found during cesarean section: case report and review of literature’’, Eur J Surg Oncol 2010;36: 789-91. doi: 10.1016/j.ejso.2010.06.019.
A25. C. Ficicioglu, G. Yildirim, R. Attar, B. Kumbak, N. Yesildaglar., ‘’The significance of the number of CGG repeats and autoantibodies in premature ovarian failure’’, Reprod Biomed Online 2010;20:776-82. doi: 10.1016/j.rbmo.2010.02.011.
A26. B. Kumbak, I. Erdem Atak, R. Attar, G. Yildirim, N. Yesildaglar, C. Ficicioglu., ‘’Psychological influence of male factor infertility on men who are undergoing assisted reproductive treatment: A preliminary study in a Turkish population’’, J Reprod Med 2010;55:417-22. 
A27. B. Kumbak, L. Sahin., ‘’Ethanol sclerotherapy for ovarian endometriomas before ovarian stimulation’’, Reprod Biomed Online 2010;20:163;auyhor reply 164. doi: 10.1016/j.rbmo.2009.10.003. 
A28. B. Kumbak, H. Akbas, L. Sahin, G. Karlikaya, H. Karagozoglu, S. Kahraman., ‘’Ovarian stimulation in women with high and low body mass index: GnRH agonist versus GnRH antagonist’’, Reprod Biomed Online 2010; 20: 314-9. doi: 10.1016/j.rbmo.2009.11.027.
A29. B. Kumbak, L. Sahin., ‘’Elevated maternal serum alpha-fetoprotein levels in patients with subchorionic hematoma’’, J Matern Fetal Neonatal Med 2010;23:717-9. doi: 10.3109/14767050903366093.
A30. G. Yildirim, R. Attar, F. Ozkan, B. Kumbak, C. Ficicioglu, N. Yesildaglar., ‘’The effects of letrozole and melatonin on surgically induced endometriosis in a rat model: a preliminary study’’, Fertil Steril 2010;93:1787-92. doi: 10.1016/j.fertnstert.2009.09.021.
A31. C. Ficicioglu, B. Kumbak, O. Akcin, R. Attar, G. Yildirim, N. Yesildaglar., ‘’Comparison of follicular fluid and serum cytokine concentrations in women undergoing assisted reproductive treatment with GnRH agonist long and antagonist protocols’’, Gynecol Endocrinol 2010;26:181-6. doi: 10.1080/09513590903215557.
A32. B. Kumbak, U. Ulug, B. Erzik, H. Akbas, M. Bahceci., ‘’Early clinical pregnancy loss rate in poor responder patients does not change compared to age-matched normoresponders’’, Fertil Steril 2009;91:106-9. doi: 10.1016/j.fertnstert.2007.11.009.  
A33. B. Kumbak, S. Kahraman., ‘’Efficacy of metformin supplementation during ovarian stimulation of lean PCOS patients undergoing in vitro fertilization’’, Acta Obstet Gynecol Scand 2009;88:563-8. doi: 10.1080/00016340902835919.
A34. B. Kumbak, H.F. Erden, S. Tosun, H. Akbas, U. Ulug, M. Bahceci., ‘’Outcome of assisted reproduction treatment in patients with an endometrial thickness less than 7mm’’, Reprod Biomed Online 2009;18: 79-84. 
A35. B. Kumbak, H. Akbas, G. Karlikaya, H. Karagozoglu, S. Ozkan, S. Kahraman., ‘’Assisted Reproductive Treatment Outcome in TESE-ICSI Cycles with Female Poor Response: A Report of 8 Years’ Duration’’, J Reprod Med 2009;54: 691-7.
A36. B. Kumbak, L. Sahin., ‘’Woman age and morphologic pattern should be taken into consideration while talking about "thin" endometrium’’, Fertil Steril 2009;92: e38; author reply e39. doi: 10.1016/j.fertnstert.2009.05.034.
A37. B. Kumbak, S. Kahraman., ‘’Management of prestimulation ovarian cysts during assisted reproductive treatments: impact of aspiration on the outcome’’,  Arch Gynecol Obstet 2009;279: 875-80. doi: 10.1007/s00404-008-0837-7. 
A38. B. Kumbak, S. Kahraman, G. Karlikaya, S. Lacin, A. Guney., ‘’In vitro fertilization in normoresponder patients with endometriomas: comparison with basal simple ovarian cysts’’, Gynecol Obstet Invest 2008;65: 212-6.
A39. B. Kumbak, E. Oral., ‘’Quality of residual follicles may depend on the etiology of "declining" ovarian function?’’, Fertil Steril 2007;88:1480-1; author reply 1481.
A40. B. Kumbak, S. Kahraman., ‘’Women with hypogonadotropic hypogonadism: cycle characteristics and results of assisted reproductive techniques’’, Acta Obstet Gynecol Scand 2006;85:1453-7.
A41. N. Findikli, S. Kahraman, Y. Saglam, C. Beyazyurek, S. Sertyel, G. Karlikaya, H. Karagozoglu, B. Aygun., ‘’Embryo aneuploidy screening for repeated implantation failure and unexplained recurrent miscarriage’’, Reprod Biomed Online 2006;13: 38-46.
A42. B. Kumbak, E. Oral, G. Karlikaya, S. Lacin, S. Kahraman., ‘’Serum estradiol and B-HCG measurements after day 3 or 5 embryo transfers in interpreting pregnancy outcome’’, Reprod Biomed Online 2006;13; 459-64.
A43 B. Kumbak, E. Oral, S. Kahraman, G. Karlikaya, H. Karagozoglu., ‘’Young patients with diminished ovarian reserve undergoing assisted reproductive treatments: A preliminary report’’, Reprod Biomed Online 2005;11: 294-9. 
A44. I. Cepni, B. Kumbak, P. Ocal, M. Idil, F. Aksu., ‘’Infertility due to intrauterine residual fetal bone fragments’’, J Clin Ultrasound 2004;32: 253-5.
A45. F. Demirkiran, B. Kumbak, T. Bese, M. Arvas, A. Benian, S. Aydin, H. Uzun, C. Sanioglu, K. Aydinli, D. Kosebay., ‘’Vascular endothelial growth factor in adnexial masses’’, Int J Obstet Gynecol 2003;83:53-