Areas of Expertise
- Hematopoietic stem cell transplantation
- Leukemias
- Lymphoma
- Neuroblastoma
- Thalassemia
- Blood transfusion
- Bone marrow failure disorders
- Benign hematology
Education & Specialty Training
1998–2005 Marmara University, Faculty of Medicine, English Program – Bachelor/Master
2005–2010 Okmeydanı Training and Research Hospital, Department of Pediatrics – Doctorate / Specialty / Medical Expertise
2013–2016 Ege University, Faculty of Medicine, Department of Pediatric Hematology and Oncology – Subspecialty
Experience
2018 Çanakkale Onsekiz Mart University, Faculty of Medicine – Assistant Professor
2018–2024 Acıbadem Mehmet Ali Aydınlar University, Faculty of Medicine – Assistant Professor
2018–2024 Acıbadem Altunizade Hospital – Pediatric Bone Marrow Transplantation
Courses & Certifications
1 April 2021 – Controversial Topics and Difficult Cases Course (Turkish Hematology Association), Virtual Congress
6 February 2021 – Central Nervous System Tumors Course-1 (Turkish Pediatric Hematology Association), Online Meeting
28 November 2020 – TPOG Long-Term Follow-Up Guide UDİR Course-1 (Turkish Pediatric Hematology Association), Webinar
22–23 March 2019 – Medical Faculty Educator Development Basic Course (Acıbadem University), Istanbul
Sep 2017–Mar 2018 – Transfusion Medicine–Blood Banking and Hemapheresis Master Class (Turkish Hematology Association, Blood Science Academy), Izmir
25 March 2017 – Pediatric Solid Tumors Course (Turkish Pediatric Oncology Association), Izmir
19–20 November 2016 – Leukemia School (Turkish Pediatric Hematology Association), Ankara
24 September 2016 – Bone and Soft Tissue Sarcomas Course (Turkish Pediatric Oncology Association), Ankara
19 March 2016 – Central Nervous System Tumors Course (Turkish Pediatric Oncology Association), Istanbul
19–20 December 2015 – Applied Hemostasis-Thrombosis Laboratory Course (Turkish Hematology Association), Antalya
12–13 September 2015 – Hematopoietic Stem Cell Transplantation Course (Turkish Hematology Association), Ankara
6–14 June 2015 – Medical Statistics in Clinical Research Course (Ege University), Izmir
14–15 February 2015 – Basic Immunology and Flow Cytometry Course (Turkish Hematology Association), Antalya
15–16 November 2014 – Pediatric Hematology-Oncology Bone Marrow Deficiency Course (Turkish Pediatric Hematology Association), Ankara
13–17 May 2014 – Radiotherapy Course for Pediatric Oncologists (XIII. National Pediatric Cancer Congress), Bodrum
13–17 May 2014 – Nutrition Course (XIII. National Pediatric Cancer Congress), Bodrum
15–16 February 2014 – Pediatric Hematology Subspecialty Trainees Transfusion School (Turkish Pediatric Hematology Association), Ankara
21–22 December 2013 – Basic Good Clinical Practice Course (Turkish Hematology Association), Antalya
1 March 2008 – Thyroid and Obesity Course (Istanbul University, Faculty of Medicine), Istanbul
9 February 2008 – Short Stature, Early and Late Puberty Course (Istanbul University, Faculty of Medicine), Istanbul
Professional Memberships
25 September 2015 – Turkish Hematology Association
5 June 2015 – Turkish Pediatric Hematology Association
2 February 2018 – Turkish Pediatric Oncology Association
6 September 2018 – Turkish Medical Association
International Peer-Reviewed Journal Articles
Akıncı B, Atay D, Demir Yenigürbüz F, Akçay A, Akar O, Öztürk G. Fatal disseminated Magnusiomyces clavatus infection with rash in pediatric acute lymphoblastic leukemia: A case report. Diagnostic Microbiology & Infectious Disease 2024;108:116148. doi:10.1016/j.diagmicrobio.2023.116148
Akıncı B, Demir Yenigürbüz F, Üstyol A, Ökdemir D. Thyroid Dysfunction in Beta-Thalassemia Major: Is It Related to Autoimmunity or Iron Overload? Acıbadem Univ. Sağlık Bilim. Derg. 2023;14(3):377-382. doi:10.31067/acusaglik.1097646
Güzelküçük Z, Yılmaz Karapınar D, et al. Central Nervous System thrombosis in pediatric acute lymphoblastic leukemia in Turkey: A multicenter study. Pediatric Blood and Cancer. 2023;e30425. doi:10.1002/pbc.30425
Cokyaman T, Sınmaz Y, et al. Diagnostic inexperience of Takayasu arteritis in pediatric neurology: a case report and mini-review of the literature. Osmangazi Journal of Medicine. 2023;45(1):135-141. doi:10.20515/otd.1176704
Demir Yenigürbüz D, Atay D, et al. Respiratory viral infections in the pediatric hematopoietic stem cell transplant population: progression to lower respiratory tract disease. J Pediatr Hematol Oncol. 2023;45(1):e75. doi:10.1097/MPH.0000000000002525
Akçay A, Atay D, et al. Safety and efficacy of co-transplantation of hematopoietic stem cells combined with human umbilical cord-derived mesenchymal stem cells in children with severe aplastic anemia: a single-center experience. Exp Clin Transplant. 2022;12:1114-1121. doi:10.6002/ect.2021.0027
Akıncı B, Atay D, et al. Therapeutic plasma exchange in pediatric patients with sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic stem cell transplantation: a single center experience. Exp Clin Transplant. 2022;20(7):680-688. doi:10.6002/ect.2021.0475
Yeşilipek MA, Uygun V, et al. Thalassemia-free and graft-versus-host-free survival: outcomes of hematopoietic stem cell transplantation for thalassemia major, Turkish experience. Bone Marrow Transplantation. 2022;57:760-767. doi:10.1038/s41409-022-01613-w
Akıncı B, Akçay A, et al. The impact of panel reactive antibodies and different desensitization methods on pediatric allogeneic hematopoietic stem cell transplantation outcomes. J Pediatr Hematol Oncol. 2022;44(3):689-694. doi:10.1097/MPH.0000000000002357
Akıncı B, Yenigürbüz FD, et al. Beta-thalassemia mutation types and the relationship with the demographic factors in Sanliurfa, Turkey. Family Practice and Palliative Care. 2021;6(3):105-110. doi:10.22391/fppc.805164
Atay D, Akçay A, et al. Co-transplantation of mesenchymal stromal cell and haploidentical hematopoietic stem cell with TCR αβ depletion in children with primary immunodeficiency syndromes. Pediatric Transplantation. 2021;25:e14120. doi:10.1111/petr.14120
Atay D, Akçay A, et al. Clinical study of graft-versus-host disease prophylaxis in unrelated hematopoietic stem cell transplantation for pediatric nonmalignant diseases with different doses anti-human T-lymphocyte immunoglobulin. Pediatric Transplantation. 2021;25:e14098. doi:10.1111/petr.14098
Tayfun Küpesiz F, Ocak S, et al. Evaluation of the knowledge of intern doctors on transfusion medicine in Turkey. Transfuze Hematol Dnes. 2020;26(3):201-211. doi:10.21203/rs.2.22224/v1
Karapınar DY, Şahin A, et al. Hyponatremia in children with acute lymphoblastic leukemia. J Pediatr Res. 2020;7(2):139-145. doi:10.4274/jpr.galenos.2019.46547
Yılmaz Karapinar D, Özdemir HH, et al. Management of a patient with congenital biallelic CSF3R mutation with GM-CSF. J Pediatr Hematol Oncol. 2020;42(3):e164-e166. doi:10.1097/MPH.00000000001359
Akıncı B, Hekimci Özdemir H, et al. Retrospective Evaluation of Childhood Cutaneous Mastocytosis Cases. J Pediatr Res. 2020;7(1):13-17. doi:10.4274/jpr.galenos.2019.98105
Karapınar DY, Patıroğlu T, et al. Homozygous c.130-131 ins A (pW44X) mutation in the HAX1 gene as the most common cause of congenital neutropenia in Turkey: Report from the Turkish Severe Congenital Neutropenia Registry. Pediatr Blood Cancer. 2019;66(10):e27923. doi:10.1002/pbc.27923
Akıncı B, Yasar AS, et al. Fertility in patients with thalassemia and outcome of pregnancies: a Turkish experience. Turk J Haematol. 2019;36(4):274-277. doi:10.4274/tjh.galenos.2019.2019.0025
Yazal Erdem A, Demir Yenigürbüz FD, et al. Refugee children with beta-thalassemia in Turkey: Overview of demographic, socioeconomic, and medical characteristics. Pediatr Blood Cancer. 2019;66:e27636. doi:10.1002/pbc.27636
Yılmaz Karapınar D, Akıncı B, et al. Congenital neutropenia patient with biallelic CSF3R mutation responding to CCSF. J Pediatr Hematol Oncol. 2019;41:e190-e192. doi:10.1097/MPH.0000000000001258
Akıncı B, Çetingül N, et al. Is there an increased risk of spinal relapse in standard-risk medulloblastoma/primitive neuroectodermal tumor patients who receive only a reduced dose of craniospinal radiotherapy? Childs Nerv Syst. 2018;34(9):1657-1662. doi:10.1007/s00381-018-3842-6
Akıncı B, Siviş ZÖ, et al. Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: a case report. Arch Argent Pediatr. 2018;116(3):e459-e462. doi:10.5546/aap.2018.eng.e459
Akıncı B, Duyu M, et al. Inferior petrosal sinus thrombosis in a child due to malposition of central venous catheter: a case report. Med Princ Pract. 2017;26(6):579-581. doi:10.1159/000484637
Avcu G, Karapinar DY, et al. Utility of serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia. Int J Infect Dis. 2017;54:8-12. doi:10.1016/j.ijid.2016.10.027
Zeytinoğlu A, Turhan A, et al. The first two ganciclovir resistant cytomegalovirus isolates from kidney and pediatric stem cell transplant recipients in Turkey. J Immunol Clin Microbiol. 2016;1(3). doi:10.5455/jicm.12.2016070
Şahbudak ZB, Karapınar DY, et al. Proven and probable invasive fungal infections in children with acute lymphoblastic leukaemia: results from an university hospital, 2005-2013. Mycoses. 2015;58:225-232. doi:10.1111/myc.12303
Kafadar İ, Akıncı AB, et al. The role of serum zinc level in febrile convulsion etiology. J Pediatr Inf. 2012;6:90-93. doi:10.5152/ced.2012.27
National Peer-Reviewed Journal Articles
Demir Yenigürbüz F, Akıncı B, et al. Endocrine complications in pediatric beta-thalassemia major patients: a single center experience. Journal of Harran University Medical Faculty. 2022;19(3):556-562. doi:10.35440/hutfd.1144199
Küpesiz TF, Andıç N, et al. Evaluation of the achievement of hematologists to transfusion medicine education with self-assessment questionnaire in Turkey. Tıp Eğitimi Dünyası. 2020;19(58):128-143. doi:10.25282/ted.658903
International Books or Book Chapters
Lanzkowsky’s Pediatric Hematology and Oncology Handbook, Chapter: Hematopoietic Stem Cell Transplantation and Cellular Therapies. 2024. Akıncı AB. Editors: Ali Bülent Antmen, Barbaros Şahin Karagün. ISBN: 978-625-99024-4-9. Pages 576-594 (Turkish translation)
Acute Leukemias in Pediatric Hematology Cases, Chapter: Successful Treatment of Hypertriglyceridemia by Plasmapheresis in a Case with Acute Lymphoblastic Leukemia. 2021. Akıncı AB. Galenos Publishing, Editors: Özbek NM, Güneş AM, Ören H, Yaralı HN. Pages 221-222 (Scientific Book, Turkish)
Acute Leukemias in Pediatric Hematology Cases, Chapter: A Case of Acute Lymphoblastic Leukemia Presenting with Type B Lactic Acidosis and Bilateral Renal Involvement. 2021. Akıncı AB. Galenos Publishing, Pages 44-46 (Scientific Book, Turkish)
Clinical Management Guide of Thalassemia, Chapter: Blood Transfusion. 2016. Akıncı AB. International Thalassemia Federation Publication, Editors: Aydınok Y, Tanyeli A, Ünal S, Kılınç Y, Malyalı D. Pages 30-43 (Book Translation, Turkish)
Education & Specialty Training
1998–2005 Marmara University, Faculty of Medicine, English Program – Bachelor/Master
2005–2010 Okmeydanı Training and Research Hospital, Department of Pediatrics – Doctorate / Specialty / Medical Expertise
2013–2016 Ege University, Faculty of Medicine, Department of Pediatric Hematology and Oncology – Subspecialty
Experience
2018 Çanakkale Onsekiz Mart University, Faculty of Medicine – Assistant Professor
2018–2024 Acıbadem Mehmet Ali Aydınlar University, Faculty of Medicine – Assistant Professor
2018–2024 Acıbadem Altunizade Hospital – Pediatric Bone Marrow Transplantation
Courses & Certifications
1 April 2021 – Controversial Topics and Difficult Cases Course (Turkish Hematology Association), Virtual Congress
6 February 2021 – Central Nervous System Tumors Course-1 (Turkish Pediatric Hematology Association), Online Meeting
28 November 2020 – TPOG Long-Term Follow-Up Guide UDİR Course-1 (Turkish Pediatric Hematology Association), Webinar
22–23 March 2019 – Medical Faculty Educator Development Basic Course (Acıbadem University), Istanbul
Sep 2017–Mar 2018 – Transfusion Medicine–Blood Banking and Hemapheresis Master Class (Turkish Hematology Association, Blood Science Academy), Izmir
25 March 2017 – Pediatric Solid Tumors Course (Turkish Pediatric Oncology Association), Izmir
19–20 November 2016 – Leukemia School (Turkish Pediatric Hematology Association), Ankara
24 September 2016 – Bone and Soft Tissue Sarcomas Course (Turkish Pediatric Oncology Association), Ankara
19 March 2016 – Central Nervous System Tumors Course (Turkish Pediatric Oncology Association), Istanbul
19–20 December 2015 – Applied Hemostasis-Thrombosis Laboratory Course (Turkish Hematology Association), Antalya
12–13 September 2015 – Hematopoietic Stem Cell Transplantation Course (Turkish Hematology Association), Ankara
6–14 June 2015 – Medical Statistics in Clinical Research Course (Ege University), Izmir
14–15 February 2015 – Basic Immunology and Flow Cytometry Course (Turkish Hematology Association), Antalya
15–16 November 2014 – Pediatric Hematology-Oncology Bone Marrow Deficiency Course (Turkish Pediatric Hematology Association), Ankara
13–17 May 2014 – Radiotherapy Course for Pediatric Oncologists (XIII. National Pediatric Cancer Congress), Bodrum
13–17 May 2014 – Nutrition Course (XIII. National Pediatric Cancer Congress), Bodrum
15–16 February 2014 – Pediatric Hematology Subspecialty Trainees Transfusion School (Turkish Pediatric Hematology Association), Ankara
21–22 December 2013 – Basic Good Clinical Practice Course (Turkish Hematology Association), Antalya
1 March 2008 – Thyroid and Obesity Course (Istanbul University, Faculty of Medicine), Istanbul
9 February 2008 – Short Stature, Early and Late Puberty Course (Istanbul University, Faculty of Medicine), Istanbul
Professional Memberships
25 September 2015 – Turkish Hematology Association
5 June 2015 – Turkish Pediatric Hematology Association
2 February 2018 – Turkish Pediatric Oncology Association
6 September 2018 – Turkish Medical Association
International Peer-Reviewed Journal Articles
Akıncı B, Atay D, Demir Yenigürbüz F, Akçay A, Akar O, Öztürk G. Fatal disseminated Magnusiomyces clavatus infection with rash in pediatric acute lymphoblastic leukemia: A case report. Diagnostic Microbiology & Infectious Disease 2024;108:116148. doi:10.1016/j.diagmicrobio.2023.116148
Akıncı B, Demir Yenigürbüz F, Üstyol A, Ökdemir D. Thyroid Dysfunction in Beta-Thalassemia Major: Is It Related to Autoimmunity or Iron Overload? Acıbadem Univ. Sağlık Bilim. Derg. 2023;14(3):377-382. doi:10.31067/acusaglik.1097646
Güzelküçük Z, Yılmaz Karapınar D, et al. Central Nervous System thrombosis in pediatric acute lymphoblastic leukemia in Turkey: A multicenter study. Pediatric Blood and Cancer. 2023;e30425. doi:10.1002/pbc.30425
Cokyaman T, Sınmaz Y, et al. Diagnostic inexperience of Takayasu arteritis in pediatric neurology: a case report and mini-review of the literature. Osmangazi Journal of Medicine. 2023;45(1):135-141. doi:10.20515/otd.1176704
Demir Yenigürbüz D, Atay D, et al. Respiratory viral infections in the pediatric hematopoietic stem cell transplant population: progression to lower respiratory tract disease. J Pediatr Hematol Oncol. 2023;45(1):e75. doi:10.1097/MPH.0000000000002525
Akçay A, Atay D, et al. Safety and efficacy of co-transplantation of hematopoietic stem cells combined with human umbilical cord-derived mesenchymal stem cells in children with severe aplastic anemia: a single-center experience. Exp Clin Transplant. 2022;12:1114-1121. doi:10.6002/ect.2021.0027
Akıncı B, Atay D, et al. Therapeutic plasma exchange in pediatric patients with sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic stem cell transplantation: a single center experience. Exp Clin Transplant. 2022;20(7):680-688. doi:10.6002/ect.2021.0475
Yeşilipek MA, Uygun V, et al. Thalassemia-free and graft-versus-host-free survival: outcomes of hematopoietic stem cell transplantation for thalassemia major, Turkish experience. Bone Marrow Transplantation. 2022;57:760-767. doi:10.1038/s41409-022-01613-w
Akıncı B, Akçay A, et al. The impact of panel reactive antibodies and different desensitization methods on pediatric allogeneic hematopoietic stem cell transplantation outcomes. J Pediatr Hematol Oncol. 2022;44(3):689-694. doi:10.1097/MPH.0000000000002357
Akıncı B, Yenigürbüz FD, et al. Beta-thalassemia mutation types and the relationship with the demographic factors in Sanliurfa, Turkey. Family Practice and Palliative Care. 2021;6(3):105-110. doi:10.22391/fppc.805164
Atay D, Akçay A, et al. Co-transplantation of mesenchymal stromal cell and haploidentical hematopoietic stem cell with TCR αβ depletion in children with primary immunodeficiency syndromes. Pediatric Transplantation. 2021;25:e14120. doi:10.1111/petr.14120
Atay D, Akçay A, et al. Clinical study of graft-versus-host disease prophylaxis in unrelated hematopoietic stem cell transplantation for pediatric nonmalignant diseases with different doses anti-human T-lymphocyte immunoglobulin. Pediatric Transplantation. 2021;25:e14098. doi:10.1111/petr.14098
Tayfun Küpesiz F, Ocak S, et al. Evaluation of the knowledge of intern doctors on transfusion medicine in Turkey. Transfuze Hematol Dnes. 2020;26(3):201-211. doi:10.21203/rs.2.22224/v1
Karapınar DY, Şahin A, et al. Hyponatremia in children with acute lymphoblastic leukemia. J Pediatr Res. 2020;7(2):139-145. doi:10.4274/jpr.galenos.2019.46547
Yılmaz Karapinar D, Özdemir HH, et al. Management of a patient with congenital biallelic CSF3R mutation with GM-CSF. J Pediatr Hematol Oncol. 2020;42(3):e164-e166. doi:10.1097/MPH.00000000001359
Akıncı B, Hekimci Özdemir H, et al. Retrospective Evaluation of Childhood Cutaneous Mastocytosis Cases. J Pediatr Res. 2020;7(1):13-17. doi:10.4274/jpr.galenos.2019.98105
Karapınar DY, Patıroğlu T, et al. Homozygous c.130-131 ins A (pW44X) mutation in the HAX1 gene as the most common cause of congenital neutropenia in Turkey: Report from the Turkish Severe Congenital Neutropenia Registry. Pediatr Blood Cancer. 2019;66(10):e27923. doi:10.1002/pbc.27923
Akıncı B, Yasar AS, et al. Fertility in patients with thalassemia and outcome of pregnancies: a Turkish experience. Turk J Haematol. 2019;36(4):274-277. doi:10.4274/tjh.galenos.2019.2019.0025
Yazal Erdem A, Demir Yenigürbüz FD, et al. Refugee children with beta-thalassemia in Turkey: Overview of demographic, socioeconomic, and medical characteristics. Pediatr Blood Cancer. 2019;66:e27636. doi:10.1002/pbc.27636
Yılmaz Karapınar D, Akıncı B, et al. Congenital neutropenia patient with biallelic CSF3R mutation responding to CCSF. J Pediatr Hematol Oncol. 2019;41:e190-e192. doi:10.1097/MPH.0000000000001258
Akıncı B, Çetingül N, et al. Is there an increased risk of spinal relapse in standard-risk medulloblastoma/primitive neuroectodermal tumor patients who receive only a reduced dose of craniospinal radiotherapy? Childs Nerv Syst. 2018;34(9):1657-1662. doi:10.1007/s00381-018-3842-6
Akıncı B, Siviş ZÖ, et al. Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: a case report. Arch Argent Pediatr. 2018;116(3):e459-e462. doi:10.5546/aap.2018.eng.e459
Akıncı B, Duyu M, et al. Inferior petrosal sinus thrombosis in a child due to malposition of central venous catheter: a case report. Med Princ Pract. 2017;26(6):579-581. doi:10.1159/000484637
Avcu G, Karapinar DY, et al. Utility of serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia. Int J Infect Dis. 2017;54:8-12. doi:10.1016/j.ijid.2016.10.027
Zeytinoğlu A, Turhan A, et al. The first two ganciclovir resistant cytomegalovirus isolates from kidney and pediatric stem cell transplant recipients in Turkey. J Immunol Clin Microbiol. 2016;1(3). doi:10.5455/jicm.12.2016070
Şahbudak ZB, Karapınar DY, et al. Proven and probable invasive fungal infections in children with acute lymphoblastic leukaemia: results from an university hospital, 2005-2013. Mycoses. 2015;58:225-232. doi:10.1111/myc.12303
Kafadar İ, Akıncı AB, et al. The role of serum zinc level in febrile convulsion etiology. J Pediatr Inf. 2012;6:90-93. doi:10.5152/ced.2012.27
National Peer-Reviewed Journal Articles
Demir Yenigürbüz F, Akıncı B, et al. Endocrine complications in pediatric beta-thalassemia major patients: a single center experience. Journal of Harran University Medical Faculty. 2022;19(3):556-562. doi:10.35440/hutfd.1144199
Küpesiz TF, Andıç N, et al. Evaluation of the achievement of hematologists to transfusion medicine education with self-assessment questionnaire in Turkey. Tıp Eğitimi Dünyası. 2020;19(58):128-143. doi:10.25282/ted.658903
International Books or Book Chapters
Lanzkowsky’s Pediatric Hematology and Oncology Handbook, Chapter: Hematopoietic Stem Cell Transplantation and Cellular Therapies. 2024. Akıncı AB. Editors: Ali Bülent Antmen, Barbaros Şahin Karagün. ISBN: 978-625-99024-4-9. Pages 576-594 (Turkish translation)
Acute Leukemias in Pediatric Hematology Cases, Chapter: Successful Treatment of Hypertriglyceridemia by Plasmapheresis in a Case with Acute Lymphoblastic Leukemia. 2021. Akıncı AB. Galenos Publishing, Editors: Özbek NM, Güneş AM, Ören H, Yaralı HN. Pages 221-222 (Scientific Book, Turkish)
Acute Leukemias in Pediatric Hematology Cases, Chapter: A Case of Acute Lymphoblastic Leukemia Presenting with Type B Lactic Acidosis and Bilateral Renal Involvement. 2021. Akıncı AB. Galenos Publishing, Pages 44-46 (Scientific Book, Turkish)
Clinical Management Guide of Thalassemia, Chapter: Blood Transfusion. 2016. Akıncı AB. International Thalassemia Federation Publication, Editors: Aydınok Y, Tanyeli A, Ünal S, Kılınç Y, Malyalı D. Pages 30-43 (Book Translation, Turkish)
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