Assoc. Prof. MD. Doğaç Okşen

Education and Specialization

• 2015 - Bachelor's Degree - Medical Doctor - Istanbul University Cerrahpaşa Faculty of Medicine

• 2020 - Medical Specialization in Cardiology, Istanbul University - Cerrahpaşa Cardiology Institute

Experience

• Kars Harakani State Hospital – Emergency Service (2015 – 2016)

• Istanbul University Cerrahpaşa Cardiology Institute, Research Assistant (2016 – 2020)

• Siirt Kurtalan State Hospital, Cardiology Specialist (2020 – 2021)

• Siirt Training and Research Hospital, Cardiology Specialist (2020 – 2021)

Professional Memberships

• Turkish Society of Cardiology

• European Society of Cardiology (ESC)

Courses and Certificates

• Good Clinical Practice E-Learning Training 14.06.2016

7.1. Articles Published in International Peer-Reviewed Journals

• Dogac Oksen, Mert Sarilar, Gursu Demirci, Ismail Haberal, Okay Abaci. In-hospital and long-term outcomes of ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention. Koşuyolu Heart J. 0000; 1(1): 000. doi:10.51645/khj.2021.m54. (Article in Press)
• Oktay V, Keskin B, Serin E, Oksen D, Kaya A, Ozkan AA. Comparison of transradial versus transfemoral diagnostic coronary angiography in terms of oxidative stress: Which option is more physiological? European Journal of Inflammation. January 2021. doi:10.1177/20587392211028073.
• Yilmaz Ak H, Özşahin Y, Yesiltas MA, Haberal İ, Kahraman S, Oksen D, Yildiz M. Comparison of Demographic Profile, Laboratory, Epidemiology and Clinical Outcomes in Patients with Native Valve and Prosthetic Valve Endocarditis. Heart Surg Forum. 2021 Jun 11;24(3): E534-E543. doi: 10.1532/hsf.3715. PMID: 34173758.
• Sit O, Oksen D, Atici A, Barman HA, Alici G, Pala AS, Tekin EA, Meke A, Borahan S, Gungor B. Prognostic significance of $\text{Tp-e}$ interval and $\text{Tp-e/QTc}$ ratio in patients with COVID-19. Eur Rev Med Pharmacol Sci. 2021 Apr;25(8):3272-3278. doi: 10.26355/eurrev_202104_25736. PMID: 33928614.
• Kalkan ME, Yildiz M, Ak HY, Zencirkiran Agus H, Ozsahin Y, Aykan AC, Oksen D. Safety of low-dose prolonged infusion of tissue plasminogen activator therapy in patients with thromboembolic events in the intensive care unit. Kardiologiia. 2020 Aug 11;60(7):86-90. doi: 10.18087/cardio.2020.7.n1091.
• Mustafa Yıldız, Gözde Mümin, Doğaç Okşen, Sinan Oral. Principles and Techniques of the Three-Dimensional Electroanatomic Cardiac Mapping Approach in the Treatment of Intractable Atrial Macroreentrant Tachycardia Ablations. Koşuyolu Heart J. 2018; 21(2): 108-110. doi:10.5578/khj.66206.
• Hülya Yılmaz Ak, Mustafa Yıldız, Nurgül Yurtseven, Deniz Özsoy, Doğaç Okşen, Hakkı Kürşat Çetin. Relation of Troponin I Levels with Postoperative Mortality and Morbidity Rates in Patients Followed in Intensive Care Unit After Congenital Cardiac Surgery Whose Ages Between 7 Days and 16 Years Old. Koşuyolu Heart J. 2018; 21(1): 043-048. doi:10.5578/khj.60771.
• Yildiz M, Yilmaz Ak H, Oksen D, Oral S. Anesthetic Management In Electrophysiology Laboratory: A Multidisciplinary Review. J Atr Fibrillation. 2018 Feb 28;10(5):1775. doi: 10.4022/jafib.1775.
• Yildiz M, Oksen D, Behnes M, Akin I. Contribution and Value of Biomarkers in Acute Aortic Syndromes. Curr Pharm Biotechnol. 2017;18(6):495-498. doi: 10.2174/1389201018666170615081727.
• Mustafa Yildiz, Yasemin Ozsahin, Hulya Yilmaz Ak, Dogac Oksen. Isolated right ventricular noncompaction in an adult woman with severe pulmonary hypertension following at the intensive care unit. Koşuyolu Heart J. 0000; 1(1): 000. doi:10.51645/khj.2021.m148. (Article in Press)

7.2. Papers Presented at International Scientific Meetings and Published in Proceedings

• Ece Yiğit, Dogac Oksen, Sema Basat. EVALUATION OF THE RELATIONSHIP BETWEEN CARDIOVASCULAR RISK AND FRACTURE RISK IN PATIENTS AGED 65-75. 3rd INTERNATIONAL CONGRESS OF MULTIDISCIPLINARY STUDIES IN MEDICAL SCIENCES. August 17, 2021 / Ankara, TURKEY.
• Dogac Oksen, Veysel Oktay. INFLUENCE OF E-CIGARETTE SMOKING ON VENTRICULAR REPOLARIZATION DISPERSION ON HEALTHY INDIVIDUALS. 16th International Update in Cardiology and Cardiovascular Surgery (UCCVS) Congress. 30 October - 1 November 2020, Antalya, Turkey.
• Dogac Oksen, Ecem Oksen, Gozde Mumin, Sukru Arslan. Evaluation of supraventricular arrhythmias among women undergoing controlled ovarian stimulation before in vitro fertilization. 36th Turkish Cardiology Congress with International Participation. 3 – 6 December 2020, Antalya, Turkey. Anatol J Cardiol, Vol: 24, (Suppl 1), December 2020.
• Dogac Oksen, Mehmet Emin Gokce, Ayca Donmez, Gursu Demirci, Sukru Arslan. Impact of Sacubitril – Valsartan on Sleep Quality in Patients with Congestive Heart Failure. 36th Turkish Cardiology Congress with International Participation. 3 – 6 December 2020, Antalya, Turkey. Anatol J Cardiol, Vol: 24, (Suppl 1), December 2020.
• Dogac Oksen, Esra Zerdeli, Ebru Serin, Bengisu Keskin, Inci Yilmaz Nakir, Zubeyir Bulat, Mert Sarilar, Veysel Oktay. Assessment of subtle left ventricular dysfunction by two dimensional strain echocardiography of HIV-1 positive individuals receiving highly active antiretroviral therapy. 36th Turkish Cardiology Congress with International Participation. 3 – 6 December 2020, Antalya, Turkey. Anatol J Cardiol, Vol: 24, (Suppl 1), December 2020.
• Evrim Kömürcü Bayrak, Hilal Şentürk, Doğaç Okşen, Cenk Eray Yıldız, Mustafa Yıldız. The importance of ANRIL expression levels in blood leukocytes of the patients with acute coronary syndrome. Anatol J Cardiol 2019; 22 (Suppl 1): 1-120. 35th Turkish Cardiology Congress with International Participation. 3 – 6 October 2019.
• Doğaç Oksen, Mert Sarılar, Veysel Oktay. Is it really necessary to say whether octogenarians to stay in the coronary intensive care unit? Anatol J Cardiol 2018; 20 (Suppl 1): 1-155. 34th Turkish Cardiology Congress with International Participation. 20 – 23 October 2018.
• Hilal Senturk, Dogac Oksen, Deniz Ozsoy, Ekrem Bilal Karaayvaz, Cenk Eray Yildiz, Mustafa Yildiz, Evrim Komurcu Bayrak. The importance of two candidate long non coding RNA expression levels on acute myocardial infarction. Anatol J Cardiol 2018; 20 (Suppl 1): 1-155. 34th Turkish Cardiology Congress with International Participation. 20 – 23 October 2018.
• Hakan Kaptanogullari, Veysel Oktay, Dogac Oksen, Vefa Celenk, Ilknur Cirali, Mustafa Yildiz. Acute effects of ultrafiltration on arterial stiffness index $\beta$ and elastic modulus in chronic hemodialysis patients. Anatol J Cardiol 2018; 20 (Suppl 1): 1-155. 34th Turkish Cardiology Congress with International Participation. 20 – 23 October 2018.
• Veysel Oktay, Doğaç Oksen, Mert Sarılar, Cüneyt Koçaş, Ahmet Yıldız. Guiding catheter induced left main coronary artery dissection treated by successfully bail-out coronary stenting. 34th Turkish Cardiology Congress with International Participation. 20 – 23 October 2018.
• Mustafa Yıldız, İbrahim Akın, Dogac Oksen, Christian Fastner, Michael Behnes, Kambis Mashayekhi, Ibrahim El Battrawy, Ralf Lehmann, Stefan Baumann, Tobias Becher, Martin Borggrefe. The left atrial appendage closure with a percutaneous path: Operative, in-hospital and echocardiographic outcomes. Anatol J Cardiol 2017; 18 (Suppl 1): 1-109. 33th TSC Abstracts/ORALS, 5 – 8 October 2017.
• Nuh Nazmi Gultekin, Ebru Serin, Dogac Oksen, Veysel Oktay, Kiymet Muammer. A Case Report: Idiopathic Progressive Polyneuropathy Accompanied by Countless Times of Acute Pulmonary Edema. 33th Turkish Cardiology Congress with International Participation. 5 – 8 October 2017.
• Dogac Oksen, Mert Sarilar, Gursu Demirci, Gkiozde Moumin, Inci Firatli. Reversable third - degree atrioventricular block induced by mirtazapine: a case report. 33th Turkish Cardiology Congress with International Participation. 5 – 8 October 2017.
• Mustafa Yildiz, Dogac Oksen, Gkiozde Moumin, Bengisu Keskin, Okay Abaci, Nazire Baskurt Aladag. Familial hypercholesterolemia patient: determined coronary plaque in real time 2D and 3D transthoracic echocardiography. 33th Turkish Cardiology Congress with International Participation. 5 – 8 October 2017.
• Veysel Oktay, Ebru Serin, Dogac Oksen, Emir Baris Okcun. Right atrial mass: myxoma causing right heart failure. 33th Turkish Cardiology Congress with International Participation. 5 – 8 October 2017.
• Ayşem Kaya, Özge Kılçarslan, Mert Palabıyık, Ümit Yaşar Sinan, Doğaç Okşen, Bengisu Keskin, Alev Arat Özkan. Implementation of Lipid Guidelines in Daily Clinical Practice. Anatol J Cardiol 2016; 16 (Suppl 1): 1-104. TSC Abstracts/ORALS October 20-23, 2016.
• Doğaç Okşen, Bengisu Keskin, Yalçın Dalgıç, Okay Abacı, Alev Arat Özkan. Ischaemia induced preexitation resolved by ranalozine. 32th Turkish Cardiology Congress with International Participation. 20 – 23 October 2016.

7.3. Papers Presented at National Scientific Meetings and Published in Proceedings

• Bengisu Keskin Meriç, Ümit Yaşar Sinan, Doğaç Okşen, Rukiye Yıldırım, Veysel Oktay, Okay Abacı, Mehmet Serdar Küçükoğlu. Kuadriküspit aort kapak: Nadir bir konjenital vaka. (Quadricuspid aortic valve: A rare congenital case.) 36th Turkish Cardiology Congress with International Participation. 3- 6 December 2020, Antalya.
• Dogac Oksen, Ebru Serin, Gürsu Demirci, Mehmet Tugay Yumuk, Veysel Oktay. Diagnostic Catheter Induced Spiral Dissection Treated by Successfully Bail-Out Coronary Stenting. 27th National Applied Interventional Cardiology Meeting. 12 – 15 November 2020.
• Dogac Oksen, Veysel Oktay. Perkütan Koroner Girişim Sonrası Üçlü Tedavi Alan Hastaları Gastrointestinal Kanamadan Nasıl Koruyalım? (How to Protect Patients Receiving Triple Therapy After Percutaneous Coronary Intervention from Gastrointestinal Bleeding?) Health Sciences University 3rd Gastroenterology Days. 19 – 20 April 2019, Istanbul.
• Veysel OKTAY, Dogac OKSEN, Mert SARİLAR, Bengisu KESKİN, Vedat SANSOY. SİSTEMATİK KORONER RİSK HESAPLAMASI (SCORE) SİSTEMİNİN ÖLÜMCÜL KARDİYOVASKÜLER HASTALIK RİSKİNİN BELİRLENMESİNDEKİ ROLÜ. (The Role of the Systematic Coronary Risk Calculation (SCORE) System in Determining the Risk of Fatal Cardiovascular Disease.) Cardiovascular Academy Winter Congress. 14 – 17 March 2019, Uludağ.
• Mustafa Yildiz, Ibrahim Akin, Dogac Oksen, Hicaz Zencikar Agus, Begum Uygur, Gokhan Demirci, Fatih Uzun, Ali Kemal Kalkan. Percutaneous Left Atrial Appendage Closure Using Double Device. 25th Applied Interventional Cardiology Congress. 3 – 6 May 2018, Antalya. (Oral Presentation).
• Hilal Şentürk, Doğaç Okşen, Deniz Özsoy, Ekrem Bilal Karaayvaz, Cenk Eray Yıldız, Mustafa Yıldız, Evrim Kömürcü-Bayrak. Miyokard Enfarktüsü Geçirmiş Erkek Hastalarda Kodlamayan RNA BAT5 İfade Düzeyleri. (Non-coding RNA BAT5 Expression Levels in Male Patients Who Have Had Myocardial Infarction.) X. Aziz Sancar DETAE Days. 29-30 November 2018, Istanbul, Turkey. (Abstract/Poster).
• Mustafa Yildiz, Sait Mesut Dogan, Ismail Haberal, Umit Yasar Sinan, Dogac Oksen, Hicaz Zencirkiran Agus, Begum Uygur, Mehmet Emin Kalkan. Successful Treatment of Dumbbell Abdominal Aortic Aneurysm Just Below Renal Arteries. 25th Applied Interventional Cardiology Congress. 3 – 6 May 2018, Antalya. (Abstract/Poster).

8. International Books or Book Chapters

• Mustafa Yildiz, Dogac Oksen, Ibrahim Akin. (2017). Cardiogenic Shock Due to Coronary Artery Stent Thrombosis. DOI: 10.5772/intechopen.68362.

9. Projects

• Researcher:
  • YILDIZ C.E., YILDIZ M., MOUMIN G., OKŞEN D., BAYRAK A.E., GEYİK F., ÇELEBİ G. (Higher Education Institutions Supported Project): Relationship between MicroRNA 125b and Micro RNA142 Expression Levels and Atherosclerosis Severity in Recent Myocardial Infarction. 2017 – 2019.
  • YILDIZ M., KESKİN B., BAYRAK A. E., OKŞEN D., YILMAZ AK H., ÇOBAN N. (Higher Education Institutions Supported Project): The Importance of Blood ANRIL Levels in the Diagnosis and Follow-up of Acute Coronary Syndrome. 2018 – 2020.

10. Clinical Trials

• A Randomized, Double-Blind, Placebo-Controlled Phase III Study Evaluating the Effects of Bempedoic Acid (ETC 1002) on the Incidence of Major Cardiovascular Events in Patients Intolerant to Statins and Having Cardiovascular Disease or at High Risk for Cardiovascular Disease. Protocol Number 1002- 043, 2017.
• A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects with Chronic Heart Failure with Reduced Ejection Fraction (GALACTIC-HF). ClinicalTrials.gov Identifier: NCT02929329, July 20, 2021.
• A Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients (NYHA Class II-IV) With Preserved Ejection Fraction (PARAGON-HF). Protocol Identifier: LCZ696D2301, June 7, 2019.
• A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects With Heart Failure and Significant Coronary Artery Disease Following an Episode of Decompensated Heart Failure (RIVAROXHFA3001). April 19, 2018.
• A 24-week, randomized, double-blind, multicenter, parallel-group, active-controlled study to evaluate the effects of LCZ696 versus individualized medical management of comorbidities on NT-proBNP, symptoms, exercise function, and safety in patients with heart failure and preserved ejection fraction.