Assoc. Prof. MD. Ebru Şen

Education

• Şişli Terakki Private High School (1987–1990), Istanbul University, Istanbul Faculty of Medicine (1990–1996)
• Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University (1996–2002)

Experience

• Department of General Surgery, Institute of Gastroenterology, Marmara University (2002–2005)
• Istanbul Faculty of Medicine, Department of Breast Surgery (2005–2006)
• Istanbul Memorial Hospital, Transplantation and General Surgery Clinic (2006–2010)
• Hospitalist Hospital (2010–2011)
• Ekotom Medical Centre and Ota Medical Centre (2012)
• Department of General Surgery, Hamidiye Şişli Etfal Training and Research Hospital (2012–2014)
• Department of General Surgery, Bakırköy Sadi Konuk Training and Research Hospital (2015–2019)
• Department of General Surgery, Başakşehir Çam ve Sakura City Hospital (2020–2026)

Foreign Language

• English

Courses and Certificates

• Advanced Endoscopic Procedures Course, Endoscopy Unit, Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University (2011)
• Oncoplastic Breast Surgery Course, Senaturk Düsseldorf Breast Cancer Centre, Germany (2013–2014)

Awards

• Graduated from Istanbul University, Istanbul Faculty of Medicine in 1996 with a good degree (10th in the year)
• First Prize for an Oral Presentation at the 16th Annual Meeting of the European Surgical Society, 2012
• First Prize for an Oral Presentation at the 6th National Congress of Endocrine Surgery, 2013
• First Prize for an Oral Presentation at the 20th International Congress on Senology and Breast Health, 2018
• Third Prize for an Oral Presentation at the 18th National Congress on Breast Diseases, 2025.

Professional Memberships

• Turkish Medical Association
• Turkish Surgical Association
• Senatürk

A. Uluslararası hakemli dergilerde yayımlanan makale ve olgu sunumları

A1. Gencosmanoglu R, Sen-Oran E. Two-step approach in the treatment of buried bumper syndrome as a late complication of percutaneous endoscopic gastrostomy. Internet Journal of Gastroenterology 2003; 2: 2.

A2. Gencosmanoglu R, Sen-Oran E, Kurtkaya-Yapicier O, Tozun N. Antral hyperplastic polyp causing intermittent gastric outlet obstruction: case report. BMC Gastroenterology 2003; 3(1): 16.

A3. Gencosmanoglu R, Sen-Oran E, Kurtkaya-Yapicier O, Avsar E, Sav A, Tozun N. Gastric polypoid lesions: analysis of 150 endoscopic polypectomy specimens from 91 patients. World Journal of Gastroenterology 2003; 9(10): 2236-2239.

A4. Gencosmanoglu R, Sen-Oran E, Kurtkaya-Yapicier O, Tozun N. Xanthelasmas of the upper gastrointestinal tract. Journal of Gastroenterology 2004; 39(3): 215-219.

A5. Gencosmanoglu R, Kurtkaya Yapicier O, E, Avsar E, Tozun N, Sen-Oran E. Mid-esophageal ulceration and candidiasis associated distal esophagitis as two distinct clinical patterns of tetracycline or doxycycline-induced esophageal injury. Journal of Clinical Gastroenterology 2004: 38(6): 484-489.

A6. Sen-Oran E, Oral C, Akin O, Yapicier OK, Tarlakazan K. A case of rectal endometriosis presenting as extramucosal rectal mass. Turkish Journal of Gastroenterology 2006; 17: 246-247.

A7. Ozmen V, Sen-Oran E, Gorgun E, Asoglu O, Igci A, Kecer M, Dizdaroglu F. Histologic and clinical outcome after laparoscopic Nissen fundoplication for gastroesophageal reflux disease and Barrett's esophagus. Surgical Endoscopy and Other Interventional Techniques 2006; 20: 226-229.

A8. Sen-Oran E, Ozmen V, Bilir A, Cabioglu N, Müslümanoğlu M, Igci A, Guney N, Kecer M. Is the thymidine labeling index a good prognostic marker in breast cancer? World Journal of Surgical Oncology 2007; 19: 5: 93.

A9. Sen-Oran E, Yankol Y, Tuzun B, Kocak B, Kanmaz T, Acarli K, Kalayoğlu M. Cadaveric liver transplantation in biliary atresia splenic malformation syndrome with the absence of retrohepatic inferior vena cava, preduodenal portal vein, and intestinal malrotation: a case report. Transplantation Proceedings 2008; 40: 313-315.

A10. Sen-Oran E, Soybir G, Mecit N, Yılmaz O, Numan F, Sönmez B, Bulut T. Rupture of traumatic gastroduodenal artery pseudoaneurysm: Case report. Chirurgia 2011; 24: 25-28.

A11. Soybir OC, Özkan GS, Sen Oran E, Tülübaş F, Yüksel M, Akyıldız AI, Bilir A, Soybir GR. Delayed Cutaneous Wound Healing in Aged Rats Compared to Younger Ones. Internatıonal Wound Journal 2012; 9: 478-487.

A12. Sen-Oran E, Soybir G, Mecit N, Oran ME, Güler M, Bulut T. Visceral Perforations Following      Lumbar Disc Surgery, A Case Report and Review of the Literature. J Universal Surg. 2012; 1: 1-6

A13. Gürdal SÖ, Saraçoğlu GV, Oran EŞ, Yankol Y, Soybir GR. The effects of educational level on breast cancer awareness: a cross-sectional study in Turkey. Asian Pacific Journal Of Cancer Prevention 2012; 13: 295-300.

A14. Oran EŞ, Gürdal SÖ, Yankol Y, Öznur M, Calay Z, Tunacı M, Soybir GR. Management of idiopathic granulomatous mastitis diagnosed by core biopsy: a retrospective multicenter study. The Breast Journal. 2013; 19: 411-418.

A15. Köksoy F, Yankol Y, Sen Oran E, Gürdal S, Yüksel M, İğdem A, Yıldırım Yazgan N, Soybir G. Preventive Effects of Enoxaparin and Hesperidin in Cerulein-induced Acute Pancreatitis in Rats. Turkish Journal Of Gastroenterology 2013; 24(6): 495-501.

A16. Oran ES, Yankol Y, Soybir GR, Karsidag T, Sakalli O, Gecgel U, Soybir OC, Soran A. Distinct postsurgical management in young and elderly breast cancer patients results in equal survival rates. Asian Pacific Journal Of Cancer Prevention 2014; 15(18): 7843-7.

A17. Aras A, Oran E, Bozkurt MA, Halıcıoğlu I, Alış H. Successful treatment of post-sleeve gastric leak with an uncovered biodegradale stent. Acta Endoscopica 2014; 44: 382-4.

A18. Uludag M, Yetkin G, Oran ES, Aygun N, Celayir F, Kartal A, Isgor A. A palsied recurrent laryngeal nerve should be explored and evaluated by intraoperative neuromonitoring during secondary thyroidectomy: report of two cases. Surg Today. 2014 Oct 19.

A19. Oran E, Seyit H, Besleyici C, Ünsal A, Alış H. Encapsulating peritoneal sclerosis as a late complication of peritoneal dialysis. Annals of Medicine and Surgery 2015; Sep: 4(3): 205-7.

A20. A Aras, Oran E, H Seyit, M Karabulut, H, Ahg. Colonoscopic perforations, what is our experience in a training hospital? Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, 2016 Feb;26(1):44-8. 

A21. Karabulut M, Afşar CH, Alış H, Oran E, Karabulut S, Akarsu C, Sahbaz AN, Giimrigollu AY Bilgin E, Ayhan FN. Evaluation of epidermal growth factor receptor senrm levels and their association with clinicopathological characteristics in patients with colorectal cancer Mol. Clin. Oncol. 7: 787-797.2017 

A22. Uludağ M, Yetkin G, Şen Oran E, Aygun N, Celayir F, Işgor A. Extralaryngeal division of the recunent laryngeal nerve: A common and asymmetric anatomical variant Turk J Surg 2017:33:164-168 

A23. E Oran, G Yetkin, N Aygtn, F Celayir, M Uludağ. Intraabdominal gossypiboma: Report of two cases Turk J Surg 2018.34: 77-79 

A24. Köneş O, Şen E. Self-Expanding Biodegradable Stents for Postoperative Upper Gastrointestinal Issues, JSLS. 2018 Apr-Jun; 22(2):20. 8.000. 1. 

A25. Gemici A.A, Ozal S, Hacoglu E, Arslan G, Sen E, Altınay S, Inci E. Relation of peritumoral, prepectoral and diffuse edema with histopathologic findings of breast cancer in preoperative 3T magnetic resonance imaging JOSAM 2019: 3(1) 49-53.

A26. Şen E, Güneş M.E, Özdemir C, Karli M, Gemici A, Altinay S. The Clinical Outcomes Regarding to Tumor-Infıltrating Lymphocytes in the Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.  Open Access Journal of Surgery 2020 11 (5);91-105.

A27. Akgün E, Alçın G, Kelten Talu EC, Çermik TF, Söylemez Akkurt T, Şen E, Arslan E. Investigation of Clinical Histopathologic Features and Metabolic Parameters of 18F-FDG PET/CT in Invasive Breast Carcinoma with a Micropapillary Component Mol Imaging Radionucl Ther. 2023 Oct 20;32(3):221-225

A28. Sen E, Canbak T, Bostanci O, Battal M. The Surgical Results of Patients With Isolated Liver Metastasis due to breast Cancer. Coll Physicians Surg Pak. 2024; 34 (5):604-609. 

A29.  Şen E, Nazlı MA, Maralcan G, Ulusoy BSS, Demircioğlu MK, Soylemez-Akkurt T, Sökücü M, Erdem GE, Yıldırım M. Who Are Suitable Patients for Omitting Breast Surgery as an Exceptional Responder in Selected Molecular Subtypes of Breast Cancer After Neoadjuvant Systemic Treatment? Medicina. 2024; Dec 31:48. doi: 10.3390/medicina61010048.

A30. Müslümanoğlu M, Cabıoğlu N, Iğci A, Karanlık H, Koçer HB, Senol K, Mantoglu B, Tukenmez M , Çakmak GK,  Ozkurt  E, Gulcelik  MA, Emiroglu S, Mollavelioglu  B, Yildirim N, Bademler S, Zengel B, Trabulus DC, Ugurlu U,  Uras C, Ilgün S,  Akgul  G, Akcan  A, Yormaz  S, Ersoy YE, Özbaş S, Dilege  E, Çitgez B, Bolukbasi  Y, Altınok  A, Dag  A, Basaran  G, Utkan NZ, Ozcinar  B, Arıcı C, AlJorani  I, Kara   H, Yiğit B, Şen E, , Erozgen F,  Soyder A, Çelik B, Kilic  HG, Zer  L, Sakman  G, Yeniay L, Atahan MK, Varol E, Veliyeva V, Goktepe  B, Velidedeoglu M, Karaman  N, Soran A, Adnan Aydiner  A, Yılmaz R,  Ibis K, Ozmen V. Combined analysis of the MF18‐02/MF18‐03 NEOSENTITURK studies: ypN‐positive disease does not necessitate axillary lymph node dissection in patients with breast cancer with a good response to neoadjuvant chemotherapy as long as radiotherapy is provided. Cancer. 2025: Jan 1;131(1):e35610. doi: 10.1002/cncr.35610

A31. Cabioglu   N, Koçer HB, Karanlik H, Gülçelik MA, Igci A, Müslümanoglu M, Uras C, Mantoglu B, Trabulus DC, Akgül G, Tükenmez M, Senol K, Özkurt E, Sen E, Karadeniz Çakmak G, Bademler S, Emiroglu S, Yildirim N, Kara H, Dag A, Dilege E, Altinok A, Basaran G, Varol E, Ugurlu Ü, Bölükbasi Y, Ersoy YE, Zengel B, Karaman N, Özbas S, Zer L, Gül Kiliç H, Agcaoglu O, Sakman G, Utkan Z, Soyder A, Akcan A, Ergün S, Yilmaz R, Aydiner A, Soran A, Ibis K, Özmen V. De-Escalation of Nodal Surgery in Clinically Node-Positive Breast Cancer. JAMA Surg. 2025 Jan 2.  doi: 10.1001/jamasurg.2024.5913.

A32.  Cabioglu N, Karanlik H, Igci A, Muslumanoglu M, Gulcelik MA, Uras C, Kocer HB, Trabulus DC, Ozkurt E, Cakmak GK, Tukenmez M, Bademler S, Yildirim N, Akgul GG, Sen E, Senol K, Emiroglu S, Citgez B, Ersoy YE, Dag A, Zengel B, Basaran G, Kara H, Dilege E, Ugurlu MU, Celik A, Ilgun S, Bolukbasi Y, Karaman N, Sakman G, Ozbas S, Kilic HG, Polat AK, Ozemir IA, Kilic B, Altınok A, Varol E, Dogan L, Akcan A, Ozcinar B, Zer L, Soyder A, Velidedeoglu M, Erozgen F, Goktepe B, Dogan M, Kebudi A, Yigit B, Celik B, Yormaz S, Arici C, Agcaoglu O, Sevinc AI, Atahan MK, Valiyeva V, Baran E, Aljorani I, Utkan Z, Yeniay L, Kivilcim T, Soran A, Aydiner A, Ibis K, Ozmen V. Breast Cancer Recurrence in Initially Clinically Node-Positive Patients Undergoing Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in the NEOSENTITURK-Trials MF18-02/18-03. Ann Surg Oncol. 2025;32: 952-966 doi: 10.1245/s10434-024-16472-6. 

A33.  Soran A, Gultekin MB, Venkatesulu BP, Barry PN, King C, Bhargava R, Karanlik H, Yildiz F, Soyder A, Goktepe B, Senol K, Guzel C, Sen E, Yeniay L, Dag A, Trabulus DC, Coskun A, Veliyeva H, Utkan Z, Demirors B, Sezgin E, Vargo JA. Biologically Informed Decision-Making for PMRT in pT3N0M0 Luminal Breast      Cancers (Protocol MF22-02): International Multicenter Real-World Data. Clin Breast Cancer. 2025 Oct;25(7):e887-e896.   

A34. Bedir Ş, Yesilova UA, Tokoçin M, Demirel BC, Bozkaya Y, Oyman A, Guliyev M, Abbasov H, Demirci NS, Değerli E, Usul G, Sen E, Bulut G, Erdem GU. Clinicopathological Predictors of Axillary Pathological Complete Response and Its Prognostic Significance in Clinically Node-Positive (cN+), HER2-Positive Breast Cancer Following Neoadjuvant Therapy. Medicina. 2026:Jan;18:62:200. doi: 10.3390/medicina62010200. 

.          Cepni K, Ucgun TH, Ucar TD, Cepni B, Uygur A, Sen E, Ozkaya H, Kiziltan HS. Predictive Role of Pre-Radiotherapy D-Dimer and Inflammatory Markers in Monitoring Outcomes After Treatment in Hormone-Positive Breast Cancer.  Diagnostics:2026: Feb;16(4):582

B. Ulusal hakemli dergilerde yayımlanan makale ve olgu sunumları

B1. Yamaner S, Şen E, Akyüz A, Bulut T, Buğra D. Appendiks adenokarsinomu (iki olgu nedeniyle). Kolon Rektum Hastalıkları Dergisi 1999; 9(2): 75-76

B2. Asoğlu O, Müslümanoğlu M, Karanlık H, Şen-Oran E, İğci A, Keçer M, Özmen V, Parlak M. İleri evre rektum kanserinde preoperatif kemoradyoterapinin etkinliği. Çağdaş Cerrahi Dergisi 2003; 17(3): 150-155

B3. Şen-Oran E, Gençosmanoğlu R. Midenin hiperplastik polipleri: tanı, tedavi ve izlemde güncel yaklaşımlar. Güncel Gastroenteroloji 2003; 7: 127-135

B4. Asoğlu O, Özmen V, Şen-Oran E, İğci A, Müslümanoğlu M, Keçer M, Parlak M, Karanlık H. Mide kanseri tedavisinde genişletilmiş lenf bezi diseksiyonu sağ kalımı etkiliyor mu? Çağdaş Cerrahi Dergisi 2003; 18(1): 9-16

B5. Kanmaz T, Şen-Oran E, Yankol Y, Acarlı K, Kalayoğlu M. Sirozda cerrahi tedavi. Türkiye Klinikleri Dahili Tıp Bilimleri Gastroenterohepatoloji 2007; 3: 52-64

B6. Şen-Oran E, Nesimi M, Calay Z, Iğdem S, Soybir G. İntrakistik papiller meme karsinomu: Olgu sunumu. Meme Sağlığı Dergisi 2010; 12: 84-87

 Yazgan-Yıldırım N, İlgün AS, Şen Oran E, Yankol Y, Özkan S, Gönüllü D, Soybir G. Ferda Nihat Köksoy. Meme kanseri evrelemesinde tümör çapı yerine tümör hacminin ölçümü daha mı faydalıdır? Meme Sağlığı Dergisi 2012; 8: 130-133

   Sen-Oran E, Gürdal S, Soybir G. Mastitler. Meme Sağlığı Dergisi 2013; 9: 1-4

B9. Ebru Oran, Gürkan Yetkin, Mehmet Mihmanlı, Fevzi Celayir, Nurcihan Aygün. Tiroidektomi sırasında paratiroid ototransplantasyonu yapılan hastalarda hipokalsemi riski. Ulusal Cerrahi Dergisi. 2016;32: 6-10

B10. Karabulut S, Karabulut M , Alış H, Dağoğlu N, Tambaş M, Kapan S, Oran E, Oğuz H, Taş F. Pankreas Adenokanserli Hastalarda Serum Ekstrasellüler Matriks Proteinlerinin Prognostik ve Prediktif Değerinin Araştırılması. Bakırköy Tıp Dergisi 2016;12:24-32.

B11. Gemici AA, Özal ST, Şen E, Hocaoğlu E, Inci E. Evaluation of Information and Practices About Breast Cancer Screening Performed in Women Presented to a University Hospital in Istanbul. Med J Bakirkoy 2020;16(2):174-81. doi: 10.5222/BMJ.2020.57441

B.12. Calim-Gurbuz B, Soylemez-Akkurt T, Eren H, Izol-Ozmen H, Şen E, Pehlivanoglu B. Perivascular invasion: a candidate prognostic parameter in breast cancer. Medeni Med J. 2024; 39:302-308.