Assoc. Prof. MD. Hakan Düğer

Education And Specialization

• 2006-2012 Gazi University Faculty Of Medicine
• 2012-2017 Uludağ University Faculty Of Medicine Hospital Internal Medicine
• 2017-2018 Ankara Numune Training And Research Hospital Endocrinology And Metabolic Diseases
• 2018-2021 Ankara Dışkapı Yıldırım Beyazıt Training And Research Hospital Endocrinology And Metabolic Diseases

Experience

• 2012-2017 Bursa Uludağ University Internal Medicine Residency
• 2017-2017 Şanlıurfa Mehmet Âkif İnan Training And Research Hospital Internal Medicine Specialist
• 2017-2018 Ankara Numune Training And Research Hospital Endocrinology And Metabolic Diseases Residency
• 2018-2021 Ankara Dışkapı Training And Research Hospital Endocrinology And Metabolic Diseases Residency
• 2021-2023 Kilis Prof Dr Alâeddin Yavaşça State Hospital Endocrinology And Metabolic Diseases Specialist
• 2023-2023 Gaziantep Private Defa Life Hospital Endocrinology And Metabolic Diseases Specialist

Professional Memberships

• Turkish Physicians Union
• Turkish Society Of Endocrinology And Metabolic Diseases
• Turkish Diabetes Association
• Clinical Endocrinology And Diabetes Association

Articles Published In International Peer-Reviewed Journals

• 1. Düğer H, Bostan H, Deryol Hy, İmga Nn, Uçan B, Çalapkulu M, Hepşen S, Akhanlı P, Gül Ü, Sencar Me, Çakal E, Özdemir Ş, Kızılgül M. Paradoxical Gh Increase During Oral Glucose Load May Predict Overall Remission In Acromegalic Patients. Growth Horm Igf Res. 2022 Dec;67:101501. Doi: 10.1016/J.Ghir.2022.101501.
• 2. Düğer H, Kızılgül M, Akhanlı P, Çalapkulu M, Bostan H, Hepşen S, Gül Ü, Sencar Me, Çakal E, Uçan B. The Role Of Elastography In The Assessment Of Thyroid Nodules In Acromegaly. Turk J Med Sci. 2023 Feb;53(1):303-309. Doi: 10.55730/1300-0144.5585.
• 3. Düğer H, Bostan H, Gül Ü, Uçan B, Hepşen S, Sakız D, Akhanlı P, Çakal E, Kızılgül M. The Importance Of Hypophosphatemia In The Clinical Management Of Primary Hyperparathyroidism. J Endocrinol Invest. 2023 Sep;46(9):1935-1940. Doi: 10.1007/S40618-023-02064-W. Epub 2023 Mar 16. Pmıd: 36929458.
• 4. Düğer H, Uçan B, Çalışkan M, Bostan H, Demirci T, Gül Ü, Çakal E, Kızılgül M. Hypomagnesemia May Be Associated With Symptomatic Disease In Patients With Primary Hyperparathyroidism. Endocrine. 2023 Nov 3.
• 5. Kizilgul M, Duger H, Nasiroglu Nı, Sencar E, Hepsen S, Akhanli P, Berker D, Cakal E, Bostan H, Ucan B. Efficacy Of Cabergoline Add-On Therapy In Patients With Acromegaly Resistance To Somatostatin Analogs Treatment And The Review Of Literature. Arch Endocrinol Metab. 2022 May 25;66(3):278–85. Doi: 10.20945/2359-3997000000481.
• 6. Bostan H, Duger H, Akhanli P, Calapkulu M, Turkmenoglu Tt, Erdol Ak, Duru Sa, Sencar Me, Kizilgul M, Ucan B, Ozbek M, Cakal E. Cushing’s Syndrome Due To Adrenocorticotropic Hormone-Secreting Metastatic Neuroendocrine Tumor Of Unknown Primary Origin: A Case Report And Literature Review. Hormones (Athens). 2022 Mar;21(1):147-154. Doi: 10.1007/S42000-021-00316-Z.
• 7. Ucan B, Kizilgul M, Karci Ac, Duger H, Erkam Sencar M, Imga Nn, Demirci T, Berker D, Erman Cakal. The Prevalence Of Cancer And Its Relation To Disease Activity In Patients With Acromegaly: Two Centers’ Experience. Endocr Pract. 2021 Jan;27(1):51-55. Doi: 10.4158/Ep-2020-0398. Epub 2020 Nov 18. Pmıd: 33475501.
• 8. Uçan B, Şahin M, Önal B, Kızılgül M, Düğer H, Sencar Me, Çakal E, Özbek M. Assessment Of Diagnostic Value Of Preoperative Elastography In Thyroid Nodules Having Indeterminate Cytology Results. Turk J Med Sci. 2021 Dec 13;51(6):2924-2930. Doi: 10.3906/Sag-2101-246.
• 9. Sencar Me, Hepsen S, Çalapkulu M, Bostan H, Sakiz D, Ozturk Unsal I, Duger H, Kizilgul M, Ucan B, Taskin Turkmenoglu T, Ozbek M, Cakal E. The Value Of Routine Measurement Of Serum Calcitonin On Insufficient, Indeterminate, And Suspicious Thyroid Nodule Cytology. Bosn J Basic Med Sci. 2022 Feb 1;22(1):118-123. Doi: 10.17305/Bjbms.2021.5756.
• 10. Sencar Me, Calapkulu M, Sakiz D, Akhanli P, Hepsen S, Duger H, Unsal Io, Kizilgul M, Cakal E. The Contribution Of Ultrasonographic Findings To The Prognosis Of Subacute Thyroiditis. Arch Endocrinol Metab. 2020 May-Jun;64(3):306-311. Doi: 10.20945/2359-3997000000253.
• 11. Kızılgül M, Bayır Ö, Uçan B, Akhanlı P, Düğer H, Sencar Me, Kertmen H, Yılmazer D, Yazılıtaş D, Saylam G, Korkmaz Mh, Çakal E. Metastatic Diffuse Follicular Variant Papillary Thyroid Cancer Without Cervical Lymph Node Metastasis Presenting With Symptoms Related To Hypopituitarism. Einstein (Sao Paulo). 2023 Jul 21;21: Erc0229. Doi: 10.31744/Einstein_Journal/2023rc0229.
• 12. Kizilgul M, Karakis R, Dogan N, Bostan H, Yapici Mm, Gul U, Ucan B, Duman E, Duger H, Cakal E, Akin O. Real-Time Detection Of Acromegaly From Facial Images With Artificial Intelligence. Eur J Endocrinol. 2023 Jan 10;188(1):Lvad005. Doi: 10.1093/Ejendo/Lvad005.
• 13. Hepşen S, Akhanlı P, Düğer H, Çalapkulu M, Uçan B, Sencar Me, Sakız D, Ünsal İö, Bayram Sm, Özbek M, Çakal E. Fatty Acid-Binding Protein-4 As A Biomarker Predicting Acromegaly-Associated Diabetes Mellitus. Turk J Med Sci. 2021 Oct;51(5):2592-2599. Doi: 10.3906/Sag2011-317.
• 14. Hepsen S, Akhanli P, Sencar Me, Duger H, Sakiz D, Kizilgul M, Ozturk Unsal I, Ucan B, Ozbek M, Cakal E. The Evaluation Of Low- And Highdose Steroid Treatments In Subacute Thyroiditis: A Retrospective Observational Study. Endocr Pract. 2021 Jun;27(6):594-600. Doi: 10.1016/J.Eprac.2020.11.009.
• 15. Hepsen S, Sakiz D, Pamukcu He, Arslan Ie, Duger H, Akhanli P, Sencar Me, Unsal Io, Ucan B, Kizilgul M, Cakal E. The Assessment Of Ventricular Arrhythmia Indicators Based On Electrocardiography In Patients With Differentiated Thyroid Cancer Followed Up With Levothyroxine Suppression. Angiology. 2021 Aug;72(7):657-663. Doi: 10.1177/0003319721993343.
• 16. Çalapkulu M, Sencar Me, Unsal Io, Sakiz D, Duger H, Özbek M, Çakal E. Tumor Volume Can Be Used As A Parameter Indicating The Severity Of Disease In Parathyroid Cancer. Endocr Pract. 2021 Jul;27(7):706-709. Doi: 10.1016/J.Eprac.2021.01.006.
• 17. Çalapkulu M, Kızılgül M, Sencar Me, Düğer H, Uçan B, Çakal E, Özbek M. Avascular Necrosis Of The Femoral Head Due To Low-Dose Corticosteroid Used In A Patient With Panhypopituitarism: A Case Report And Literature Review. Jt Dis Relat Surg. 2020;31(2):390-394. Doi: 10.5606/Ehc.2020.72773.
• 18. Calapkulu M, Sencar Me, Sakiz D, Duger H, Ozturk Unsal I, Ozbek M, Cakal E. The Prognostic And Diagnostic Use Of Hematological Parameters In Subacute Thyroiditis Patients. Endocrine. 2020 Apr;68(1):138-143. Doi: 10.1007/S12020-019-02163-W
• 19. Calapkulu M, Sencar Me, Duger H, Bayram Sm, Unsal Io, Cakal E, Ozbek M. Coexistence Of Type-1 Diabetes Mellitus And Papillary Thyroid Carcinoma. Curr Diabetes Rev. 2020;16(7):787-789. Doi:
• 20. Bostan H, Sencar Me, Calapkulu M, Hepsen S, Akhanli P, Duger H, Ucan B, Kizilgul M, Ozturk Unsal I, Ozbek M, Cakal E. The Predictive Value Of Hematologic Parameters In The Risk Of Thyroid Malignancy In Cases With Atypia/Follicular Lesion Of Undetermined Significance. Eur Arch Otorhinolaryngol. 2022 Aug;279(8):4077-4084. Doi: 10.1007/S00405-021-07248-9.
• 21. Bostan H, Sencar Me, Calapkulu M, Hepsen S, Duger H, Ozturk Unsal I, Ozbek M, Cakal E. Two Important Issues In Subacute Thyroiditis Management: Delayed Diagnosis And Inappropriate Use Of Antibiotics. Eur Thyroid J. 2021 Jul;10(4):323-329. Doi: 10.1159/000513745.
• 22. Akhanlı P, Hepşen S, Uçan B, Düğer H, Bostan H, Kızılgül M, Sencar Me, Çakal E. The Evaluation Of Breast Findings Detected Through Different Visualisation Techniques In Acromegaly Patients - A Retrospective Study. Turk J Med Sci. 2021 Dec 13;51(6):3073-3081. Doi: 10.3906/Sag-2105-35.
• 23. Kaya Çelik E, Er S, Keseroğlu K, Öner F, Düğer H, Uçan B, Kızılgül M, Çetin Ş, Saylam G. Disrupted Harmony Of The Skull Skeleton: Middle Ear Resonance In Acromegaly. Growth Horm Igf Res. 2024 Jun;76:101594. Doi: 10.1016/J.Ghir.2024.101594. Epub 2024 May 23. Pmıd: 38833815.
• 24. Akhanli P, Hepşen S, Arslan İe, Düğer H, Bostan H, Kizilgül M, Uçan B, Çakal E. Impact Of 24-Week Dapagliflozin Treatment On Body Weight, Body Composition, And Cardiac Risk Indicators Of Patients With Type-2 Diabetes Mellitus. Turk J Med Sci. 2023 Aug 11;53(5):1178- 1184. Doi: 10.55730/1300-0144.5683. Pmıd: 38813008; Pmcıd: Pmc10763806.
• 25. Bostan H, Kizilgul M, Calapkulu M, Kalkisim Hk, Topcu Fbg, Gul U, Duger H, Hepsen S, Ucan B, Cakal E. The Prevalence And Associated Risk Factors Of Detectable Renal Morphological Abnormalities In Acromegaly. Pituitary. 2024 Feb;27(1):44-51. Doi: 10.1007/S11102-023- 01370-Z. Epub 2023 Dec 8. Pmıd: 38064149.

Articles Published In National Peer-Reviewed Journals

• 1. Düğer, Hakan; Ucan, Bekir. Pioglitazone/Exenatide/Sglt-2 Inhibitor Combination Therapy Versus Insulin Therapy In Patients With Poorly Controlled Type 2 Diabetes. Anatolian Current Medical Journal, 2024, 6.2: 121-126.
• 2. Düğer, Hakan. The Prevalence Of Hypogonadism In Male Patients With Type 2 Diabetes Mellitus And Clinically Relevant Factors. Journal Of Health Sciences And Medicine, 7.1: 53-57.
• 3. Akhanli, P., Hepsen, S., Duger, H., Kizilgul, M., Neselioglu, S., Erel, O., & Cakal, E. (2023). The Evaluation Of Dynamic Thiol/Disulfide Homeostasis In Papillary Thyroid Carcinoma.
• 4. Akhanli Pinar, Hepsen Sema, Düger Hakan, Kizilgül Muhammed, Neselioglu Salim, Erel Özcan, Çakal Erman (2023). The Evaluation Of Dynamic Thiol/Disulfide Homeostasis In Papillary Thyroid Carcinoma. Annals Of Medical Research, 30(10), 1228-1231., Doi:10.5455/Annalsmedres.2023.08.196
• 5. Düger Hakan, Ersoy Alparslan (2023). Impact Of Kidney Transplantation-Related Complications On Patient And Graft Outcomes In Early Period. Uludag Üniversitesi Tıp Fakültesi Dergisi, 49, Doi: 10.32708/Uutfd.1385050
• 6. Çalapkulu Murat, Sencar Muhammed Erkam, Öztürk Ünsal Ilknur, Sakiz Davut, Bostan Hayri, Düger Hakan, Özbek Mustafa, Çakal Erman (2022). Evaluation Of Bone Mineral Densitometry Measurements In Newly Diagnosed Acromegaly Patients. Turkish Journal Of Osteoporosis, 28, Doi: 10.4274/Tod.Galenos.2021.59489
• 7. Çalapkulu Murat, Sencar Muhammed Erkam, Öztürk Ünsal Ilknur, Düger Hakan, Özbek Mustafa, Çakal Erman (2021). Large Ganglioneuroma Case Mimicking As An Adrenal Adenoma. Turkish Journal Of Internal Medicine, 3(1), 123-126., Doi: 10.46310/Tjim.877025

Oral Presentations

• 1. Werner Syndrome As A Rare Cause Of Pituitary Insufficiency And Papillary Thyroid Carcinoma, Düger Hakan, Zengin Oguzhan, Nasiroglu Imga Narin, Berker Dilek (2018) Endobridge 2018
• 2. Overt Hypothyroidism'li Patients Levothyroxine Replacement On Proteinuria And Kidney Functions, Düger Hakan (2023).. 25. National Internal Medicine Congress
• 3. The Relationship Between Vitamin D Deficiency And Islet Cell Function In Patients With Type 2 Diabetes, Düğer Hakan (2023) 3. Dicle Internal Medicine Congress
• 4. Prevalence Of Acromegaly In Patients With Uncontrolled Type 2 Diabetes Mellitus, Topalak Sönmez Münire, Bostan Hayri, Gül Ümran, Düger Hakan, Hepsen Sema, Uçan Bekir, Çakal Erman, Kizilgül Muhammed (2022) 7. Diabetes And Associated Diseases Treatment Congress, 19-20.
• 5. Evaluation And Comparison Of Current Ecgs Of Acromegaly Patients At The Time Of Diagnosis And After Treatment With New Arrhythmia Parameters In Terms Of Ventricular Arrhythmia, Tekin Zeynep Zehra, Erken Pamukcu Hilal, Bostan Hayri, Gül Ümran, Düger Hakan, Uçan Bekir, Hepsen Sema, Intas Kadir, Çakal Erman, Akdag Seyit Ibrahim, Kayhan Sanem, Kizilgül Muhammed (2022).. 43. Turkish Endocrinology And Metabolic Diseases Congress,-
• 6. Real-Time Detection Of Acromegaly From Facial Images With Artificial Intelligence, Kizilgül Muhammed, Dogan Nurettin, Gül Ümran, Yapici Muhammed Mutlu, Bostan Hayri, Duman Elvan, Uçan Bekir, Karakis Rukiye, Düger Hakan, Akin Ömer, Çakal Erman (2022) 43. Turkish Endocrinology And Metabolic Diseases Congress
• 7. The Value Of Hematological Parameters In Predicting Thyroid Malignancy In Cases Of Atypia/Follicular Lesion Of Undetermined Significance, Bostan Hayri, Çalapkulu Murat, Sencar Muhammed Erkam, Hepsen Sema, Düger Hakan, Akhanli Pinar, Çakal Erman (2021). Endokurs-5
• 8. Effects Of Sglt-2 Inhibitors On Mpv And Other Hemogram Parameters, Akhanli Pinar, Hepsen Sema, Kizilgül Muhammed, Bilen Ayhan Sevgi, Düger Hakan, Bostan Hayri, Sencar Muhammed Erkam, Uçan Bekir, Çakal Erman (2021) 57. National Diabetes Metabolism And Nutrition Diseases Congress
• 9. A New Biomarker For Predicting Diabetes In Acromegaly Patients: Fatty Acid Binding Protein-4, Hepsen Sema, Akhanli Pinar, Düger Hakan, Çalapkulu Murat, Uçan Bekir, Sencar Muhammed Erkam, Öztürk Ünsal Ilknur, Sakiz Davut, Bayram Murat, Özbek Mustafa, Çakal Erman (2021) 42. Turkish Endocrinology And Metabolic Diseases Congress
• 10. Adrenal Hemangioma: Adrenal Incidentaloma Mimicking Adrenocortical Cancer, Düger Hakan, Çalapkulu Murat, Hepsen Sema, Akhanli Pinar, Bostan Hayri, Uçan Bekir, Kizilgül Muhammed, Çakal Erman (2021) 42. Turkish Endocrinology And Metabolic Diseases Congress
• 11. A Case Of Primary Adrenal Insufficiency Presenting With Life-Threatening Electrolyte Imbalance, Akhanli Pinar, Hepsen Sema, Düger Hakan, Bostan Hayri, Uçan Bekir, Kizilgül Muhammed, Arslan Ismail Emre, Özbek Mustafa, Çakal Erman (2021) 42. Turkish Endocrinology And Metabolic Diseases Congress
• 12. A Case Of Subacute Thyroiditis Diagnosed Concurrently With Pregnancy, Hepsen Sema, Düger Hakan, Akhanli Pinar, Bostan Hayri, Sencar Muhammed Erkam, Özbek Mustafa, Çakal Erman (2021) 42. Turkish Endocrinology And Metabolic Diseases Congress
• 13. Coexistence Of Type 1 Diabetes And Papillary Thyroid Carcinoma, Çalapkulu Murat, Düger Hakan, Sencar Muhammed Erkam, Bayram Murat, Özbek Mustafa, Çakal Erman (2019) 55. National Diabetes Metabolism And Nutrition Diseases Congress
• 14. Diabetes Autoantibodies That Became Negative During Follow-Up, Bayram Murat, Çalapkulu Murat, Düger Hakan, Sencar Muhammed Erkam (2019) 55. National Diabetes Metabolism And Nutrition Diseases Congress

Books

• 1. Clinical Endocrinology, Chapter Title:(Hyperthyroidism) (2022)., Düger Hakan, Uçan Bekir, Hipokrat, Edition Number:1, Page Count 724, Isbn:978-625-7399-38-8, Turkish
• 2. Internal Medicine, Chapter Title:(Multiple Endocrine Neoplasias) (2022)., Düger Hakan, Uçan Bekır, Hipokrat, Editor:Çifci Aydın, Dal Mehmet Sınan, Demır Mehmet Emın, Tanoglu Alpaslan, Keskek Sakır Özgür, Edition Number:1, Page Count 3830, Isbn:978-625-7399-56-2
• 3. Endocrinology And Metabolic Diseases, Chapter Title:(Parenteral Treatment In Diabetes (Glp- 1’s, Classic Insulin Therapy And Pump)) (2022)., Düger Hakan, Hipokrat, Editor:Çetin Zeynep, Edition Number:1, Page Count 402, Isbn:978-625-7399-84-5, Turkish
• 4. Internal Medicine, Chapter Title:(Male Hypogonadism) (2022)., Düger Hakan, Uçan Bekır, Hipokrat, Editor:Çifci Aydın, Dal Mehmet Sınan, Demır Mehmet Emın, Tanoglu Alpaslan, Keskek Sakır Özgür, Edition Number:1, Page Count 3830, Isbn:978- 625-7399-56-2, Turkish
• 5. Endocrine Emergencies, Chapter Title:(Adrenal Emergencies) (2021)., Düger Hakan, Uçan Bekır, Medihealth Academy, Editor:Uçan Bekır, Edition Number:1, Page Count 96, Isbn:978-605-74841-3-0, Turkish