Asst. Prof. MD. Melek Erdem

Education and Specialization

• September 1999-January 2006 Ege University Faculty of Medicine Education
• August 2007-August 2012 Uludağ University Faculty of Medicine Pediatric Health and Diseases Specialization Education
• January 2014-February 2018 Dokuz Eylül University Faculty of Medicine Subspecialty Training in Pediatric Hematology and Oncology

Experience

• May 2006-August 2007 Batman Bekirhan Health Center Post-Graduation Mandatory Service General Practitioner
• September 2012-January 2014 Mardin Kızıltepe State Hospital Post-Specialization Mandatory Service - Pediatric Health and Diseases Specialist
• May 2018-November 2020 S.B.Ü. İzmir Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital Subspecialty Residency & Post-Residency Mandatory Service & Pediatric Hematology and Oncology Department
• November 2020-June 2022 Bursa Uludağ University Faculty of Medicine Department of Pediatrics, Division of Pediatric Oncology, Lecturer Dr.

Courses and Certificates

• Turkish Hematology Association Turkish Blood Science (Hematology) Hematopoietic Stem Cell Master Class Graduate
• June 16-21, 2018 The European School of Oncology (ESO) 7th ESO-SIOP Europe Masterclass in Pediatric Oncology

Professional Memberships

• Turkish Hematology Association
• Turkish Pediatric Oncology Group
• Member of the Istanbul Medical Association

Articles Published in International Peer-Reviewed Journals:

• 1. Ersoy GZ, Aksoy BA, Erdem M, Karataş L, Aydoğdu S, Öner ÖB, Dikme G, Bozkurt C, Fışgın T. Outcomes of Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: How Do Anti-HLA Antibodies Impact?: The Impact of Anti- HLA Antibodies on Transplantation Outcomes in Thalassemia Major. Clin Transplant. 2024 Dec;38(12):e70035. doi: 10.1111/ctr.70035. PMID: 39601247.
• 2. Acar SO, Tahta N, Al IO, Erdem M, Gözmen S, Karapınar TH, Kılınç B, Celkan T, Kirkiz S, Koçak Ü, Ören H, Yıldırım AT, Arslantaş E, Ayhan AC, Oymak Y. Sirolimus is effective and safe in childhood relapsed-refractory autoimmune cytopenias: A multicentre study. Scand J Immunol. 2024 Aug;100(2):e13376. doi: 10.1111/sji.13376. Epub 2024 May 13. PMID: 38741164.
• 3. Ersoy GZ, Çipe F, Fışgın T, Aksoy BA, Öner ÖB, Hashemi N, Aydoğdu S, Erdem M, Dikme G, Murat K, Bozkurt C. The impact of Treosulfan-based conditioning for inborn errors of immunity: Is dose monitoring crucial? Clin Transplant. 2023 Sep;37(9):e15083. doi: 10.1111/ctr.15083. Epub 2023 Aug 3. PMID: 37534623.
• 4. Odaman Al I, Demirağ B, Erdem M, Genç S, Karapinar TH. A Retrospective Analysis of Clinical Characteristics, Treatment Modalities and Outcome of the Patients With Infantile Hepatic Hemangiomas: Single-center Experience From Turkey. J Pediatr Hematol Oncol. 2023 Mar 1;45(2):e259-e265. doi: 10.1097/MPH.0000000000002472. Epub 2022 May 5. PMID: 35537066.
• 5. Sezgin Melike Evim, TÜFEKÇI ÖZLEM, BAYTAN BIROL, ÖREN HALE, ÇELEBI SOLMAZ, ENER BEYZA, ÜSTÜN ELMAS KEVSER, YILMAZ SEBNEM, ERDEM MELEK, HACIMUSTAFAOGLU MUSTAFA KEMAL, MERAL GÜNES ADALET (2021). Invasive Fungal Infections in Children with Leukemia: The Clinical Features and Prognosis. Turk J Hematol (Yayın No: 7400998)
• 6. DÜZGÖL MINE, Böncüoglu Elif, KIYMET ELIF, AKASLAN KARA AYBÜKE, ERDEM MELEK, ODAMAN AL ISIK, Demirag Bengü, ZIHNI CÜNEYT, KARAPINAR TUBA HILKAY, OYMAK YESIM, MESE TIMUR, BAYRAM SÜLEYMAN NURI, DEVRIM ILKER (2021). Evaluation for Metastatic Candida Focus and Mortality at Candida-associated Catheter-related Bloodstream Infections at the Pediatric Hematology-oncology Patients.. Journal of pediatric hematology/oncology, Doi: 10.1097/MPH.0000000000002197 (Yayın No: 7296951)
• 7. ODAMAN AL ISIK, OYMAK YESIM, ERDEM MELEK, TAHTA NERYAL, OKUR ACAR SULTAN, MESE TIMUR, YILMAZER MURAT MUHTAR, GÖZMEN SALIH, ZIHNI CÜNEYT, Çalkavur Sebnem, KARAPINAR TUBA HILKAY (2021). Assessment of clinical characteristics and treatment outcomes of pediatric patients with intracardiac thrombosis: a single-center experience.. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Doi: 10.1097/MBC.0000000000001100 (Yayın No: 7296935)
• 8. ERDEM MELEK, TÜFEKÇI ÖZLEM,KIZILDAG SEFA,YILMAZ SEBNEM,KIZMAZOGLU DENIZ,EROGLU FiLIBELI BERNA (2019). Investigation of the Relationship Between Fok1 and Col1A1 Gene 1 Polymorphisms and Development of Treatment-Related Bone Complications in Children with Acute Lymphoblastic Leukemia. Turkish Journal of Hematology, 36(1), 12-18., Doi: 10.4274/tjh.galenos.2018.2018.0221 (Yayın No: 6697361)
• 9. TOLGA SEVER, LEBLEBICI ASIM, KOÇ ALTUG, BINICIER HATICE ÇILEM, OLGUN AYBÜKE,EDIZER DENIZ TUNA, ÖZDEMIR TAHA RESID, ERDEM MELEK, BASKIN YASEMIN (2019). New Insight of Tumor Microenvironment in Non-Small Cell Lung Cancer. Journal of Basic and Clinical Health Sciences(3), 113-120., Doi: 10.30621/jbachs.2019.625 (Yayın No: 6697671)
• 10. DEMIR YENIGÜRBÜZ FATMA, KIZMAZOGLU DENIZ, ATES HALIL, ERDEM MELEK, TÜFEKÇI ÖZLEM, YILMAZ SEBNEM, ÖREN HALE (2019). Analysis of apoptotic, platelet-derived, endothelial derived, and tissue factor-positive microparticles of children with acute lymphoblastic leukemia during induction therapy. Blood Coagulation Fibrinolysis, 30(4), 149-155. (Yayın No: 6697151)
• 11. YILMAZ SEBNEM, ATASEVEN EDA, DEMIR YENIGÜRBÜZ FATMA, ERDEM MELEK, ÖREN HALE (2017). FLAG Treatment with or without Idarubicin in Children with Relapsed/Refractory Acute Leukemia: A Turkish Pediatric Hematology Center Experience. Turkish Journal of Hematology, 34(1), 46- 51. (Yayın No: 6697108)

Articles Published in National Peer-Reviewed Journals:

• 1. ODAMAN AL ISIK, OYMAK YESIM, KARAPINAR TUBA HILKAY, ERDEM MELEK, GÖZMEN SALIH, TAHTA NERYAL, OKUR ACAR SULTAN, ÇAGLAR ILKNUR, BAYRAM SÜLEYMAN NURI, DEVRIM ILKER (2021). Congenital Neutropenia in Children: Evaluation of Infectious Complications, Treatment Results and Long-Term Outcome. Izmir Dr. Behçet Uz Çocuk Hast. Dergisi 2021;11(2):181-7, 11(2), Doi: 10.5222/buchd.2021.72325 (Kontrol No: 7296964)
• 2. ERDEM MELEK, TÜFEKÇI ÖZLEM, KARAPINAR TUBA HILKAY,OYMAK YESIM,BAYSAL BIRSEN,YILMAZ SEBNEM, VERGIN CANAN, ÖREN HALE (2018). The Retrospective Evaluation of Severe Hypertriglyceridemia Occurred During Therapy in Children with Acute Lymphoblastic Leukemia: Experience of Two Centers. LLM Dergi, 2(4), 84-88. (Kontrol No: 6697453)

Case Reports Published in International Peer-Reviewed Journals:

• 1. Tüfekçi Ö, Yılmaz Ş, Erdem M, Baysal B, Ören H. Isolated Mediastinal Myeloid Sarcoma after NPM1 Positive Pediatric Acute Myeloid Leukemia. Turk J Haematol. 2019 Nov 18;36(4):285-286. doi: 10.4274/tjh.galenos.2019.2018.0434.Epub 2019 Mar 12. PMID: 30859798; PMCID: PMC6863024.
• 2. Baysal B, Tüfekçi Ö, Erdem M, Yilmaz Ş, Ören H. Transient Pancytopenia and Granulocyte Abnormalities After Suicide Attempt With Colchicine in a Patient With Familial Mediterranean Fever. J Pediatr Hematol Oncol. 2019 Aug;41(6):489. doi: 10.1097/MPH.0000000000001456. PMID: 30883459.
• 3. Erdem M, Tüfekçi Ö, Yılmaz Ş, Alacacıoğlu İ, Ören H. Long-Term Follow-Up of a Case with Dyskeratosis Congenita Caused by NHP2-V126M/X154R Mutation: Genotype-Phenotype Association. Acta Haematol. 2019;141(1):28-31. doi: 10.1159/000494421. Epub 2018 Nov 23. PMID: 30472699.
• 4. Tüfekçi Ö, Erdem M, Ören H, Yilmaz Ş. Cup-like Blasts in 2 Pediatric Patients With NPM-1-Positive Acute Myeloid Leukemia. J Pediatr Hematol Oncol. 2018 May;40(4):e237-e238. doi: 10.1097/MPH.0000000000001110. PMID: 29432313.
• 5. Tüfekçi Ö, Yilmaz Bengoa Ş, Erdem M, Ören H. Induction Failure in Acute Leukemia or Parvovirus B19 Infection? J Pediatr Hematol Oncol. 2017 Oct;39(7):565. doi: 10.1097/MPH.0000000000000866. PMID: 28665873.