Assoc. Prof. MD. Özlem Özkul

Education & Specialization

• 2002–2009: Uludağ University, Faculty of Medicine, MD

• 2011–2015: Kocaeli University, Faculty of Medicine – Internal Medicine, Specialty

• 2016–2020: Sakarya University Training and Research Hospital – Medical Oncology, Subspecialty

• 2020–2022: Bağcılar Training and Research Hospital – Medical Oncology

• July 2022–Present: Istanbul Aydin University – Medical Oncology

Professional Experience

• 2009–2010: Ministry of Health, Mustafakemalpaşa Tuberculosis Unit

• 2011–2015: Kocaeli University, Department of Internal Medicine

• 2016: Şanlıurfa Mehmet Akif İnan Training and Research Hospital

• 2016–2020: Sakarya Training and Research Hospital, Department of Medical Oncology

• 2020–2022: Bağcılar Training and Research Hospital, Department of Medical Oncology

• 2022–Present: Istanbul Aydin University VM Medical Park Florya

Awards

• Second Place, Best Oral Presentation: Özkul Ö, Özkul B, Survey Study on Oncology Subspecialty Training in Turkey, March 13–14, 2021, Biomarkers and Oncologic Treatments Symposium, Online, Turkey, S-014

Professional Memberships

• Turkish Society of Medical Oncology (TTOD)

• American Society of Clinical Oncology (ASCO)

• European Society for Medical Oncology (ESMO)

Courses & Certificates

• TTOD-Tucrin: Fundamentals of Clinical Research, Izmir, Turkey, November 19–20, 2016

• ANORIST Statistical Solutions: IBM SPSS Statistics Basic Biostatistics Training, Sakarya, Turkey, December 24–25, 2016

SCI and SCI-Expanded Indexed International Peer-Reviewed Journals

• S. Alagöz, N. Eren, S.G. Özcan, Z. Atlı, Ö. Özkul, H. Belli, N. Görgülü, M. Seyyar, N. Seyahi. Impact of COVID-19 lockdown on mood status: A comparison of hemodialysis and oncology patients. Therapeutic Apheresis and Dialysis. 2021 Nov; 2021:1–9. https://doi.org/10.1111/1744-9987.13767
• İ. Hacıbekiroğlu, Ö. Özkul, E. Çakır, O. Köstek, F. Karataş, A. Esenkaya, A. Demirci, C. Bilir. Comparative assessment of three different second-line regimens in chemotherapy resistant/refractory small-cell lung cancer. JBUON. Jan-Feb 2021; 26(1):79–86. PMID: 33721436
• Y. Bakkal Temi, A.M. Sedef, S. Gökçay, H. Coşkun, S. Oskeroğlu Kaplan, Ö. Özkul, H. Mertsoylu, F. Köse. A study on basic demographic and disease characteristics of cancer-diagnosed Syrian refugees treated in the border city of Turkey, Şanlıurfa; a hospital-based retrospective case series study. JBUON. Nov-Dec 2017; 22(6):1591–1594. PMID: 29332358
• M.B. Hacıoğlu, O. Köstek, S. Karabulut, D. Taştekin, S. Sezgin Göksu, C. Alandağ, B. Akagündüz, İ. Bilgetekin, B. Caner, A.B. Şahin, B. Yıldız, F. Köse, M.A. Kaplan, A. Gülmez, E. Doğan, D.C. Güven, M. Gürbüz, Y. Ergün, M. Karaağaç, A.G. Demiray, S. Türker, T. Sakalar, Ö. Özkul, T. Akın Telli, S. Şahin, S. Kılıçkap, A. Bilici, B. Erdoğan, İ. Çiçin. Efficacy of regorafenib in the second- and third-line setting for patients with advanced hepatocellular carcinoma: A real-life multicenter study from Turkey. JBUON. 2020 Jul-Aug; 25(4):1897–1903. PMID: 33099930
• O. Köstek, M.B. Hacıoğlu, A. Sakin, T. Demir, M. Sarı, Ö. Özkul, M. Araz, A.F. Doğan, N.C. Demircan, S. Uzunoğlu, İ. Çiçin, B. Erdoğan. Regorafenib or rechallenge chemotherapy: Which is more effective in the third-line treatment of metastatic colorectal cancer? Cancer Chemother Pharmacol. 2019 Jan; 83(1):115–122. doi: 10.1007/s00280-018-3713-6
• B. Özkul, Ö. Özkul, C. Bilir. Predicting the overall survival in patients with advanced pancreatic cancer by calculating L3 skeletal muscle index derived from CT. Current Medical Imaging. 2022 Mar 3. doi: 10.2174/1573405618666220303105410
• İ.H. Sever, B. Özkul, D. Erişik Tanrıöver, Ö. Özkul, C.S. Elgormus, S.G. Gür, İ. Söğüt, Y. Uyanıkgil, E.O. Çetin, O. Erbaş. Protective effect of oxytocin through its anti-inflammatory and antioxidant role in a model of sepsis-induced acute lung injury: Demonstrated by CT and histological findings. Experimental Lung Research. 2021 Nov;47(9):426–435. https://doi.org/10.1080/01902148.2021.1992808
• M. Gürbüz, Y. Kutlu, E. Akkuş, E.B. Köksoy, N. Köse, B.B. Öven, B.O. Uluç, A.G. Demiray, D. Erdem, B. Demir, N.S. Turhal, N. Üskent, S. Akbaş, F. Selçukbiricik, A. İnal, A. Bilici, Ö.F. Ölmez, D. Çabuk, Ç. Ünal, M. Hızal, M.A.N. Şendur, M. Korkmaz, N. Karadurmuş, İ. Ertürk, S.S. Göksu, A.M. Tatlı, D.C. Güven, S. Kılıçkap, N. Paksoy, A. Aydıner, H.Y. Çınkır, Ö. Özkul, A. Öztürk, S. Ballı, Y. Kemal, A.P. Erdoğan, Ö. Er, P.F. Yumuk, A. Demirkazık. Atezolizumab combined with chemotherapy in the first-line treatment of extensive-stage small cell lung cancer: A real-life data of the Turkish Oncology Group. J Cancer Res Clin Oncol. 2022. https://doi.org/10.1007/s00432-022-04087-x

Other Indexed International Journals

• Ö. Özkul, A. Yazıcı, A.S. Aktürk, D.T. Karadağ, Ö.O. Işık, S. Tekeoğlu, A. Cefle. Are there any differences among psoriasis, psoriatic arthritis and rheumatoid arthritis in terms of metabolic syndrome and cardiovascular risk factors? European Journal of Rheumatology. 2018 Oct;6(4):174–178. https://doi.org/10.5152/eurjrheum.2019.19029
• Ö. Özkul, B. Kızılkaya, H. Eren, T. Ayaz, C. Bilir. Correlations between estimating GFR methods and oncological outcomes during cancer chemotherapy. Ortadogu Medical Journal. 2019 May;11(4):390–395. https://doi.org/10.21601/ortadogutipdergisi.499665
• Ö. Özkul, H. Morcalı, B. Kızılkaya, G. Puşuroğlu, Y. Bakkal Temi, C. Bilir. Paclitaxel-Carboplatin Based Therapy in Elderly Patients with Non-Small Cell Lung Cancer. Journal of Human Rhythm. 2017 Jun;3(2):101–104. ISSN: 2149-455X
• Ö. Özkul, B. Özkul, O. Erbaş. The investigation of ameliorating effect of methylene blue on cisplatin-induced neurotoxicity in female rats. Journal of Clinical and Experimental Investigations. 2022 Mar; em00789. https://doi.org/10.29333/jcei/11555

International Scientific Conferences – Oral and Poster Presentations

Oral Presentations

• B. Özkul, N. İnan, H.T. Sarısoy, G. Akansel, Ö. Özkul, A. Demirci. Diagnostic Performance of Diffusion Weighted Magnetic Resonance Imaging for Pericardial Effusion. European Society of Thoracic Imaging Congress, 2014, Amsterdam, Netherlands.

Poster Presentations

• B. Özkul, N. İnan, Ö. Özkul, H.T. Sarısoy, G. Akansel, A. Akça, İ. Çam. A Rare Case: Coronary Sinus Thrombosis. European Society of Thoracic Imaging, 12–14 June 2014, Amsterdam, Netherlands, P-0085.

• B. Özkul, S. Gümüştaş, Ö. Özkul, İ. Çam, A. Akça, A. Demirci. Sweet’s Syndrome: Pulmonary Involvement. European Society of Thoracic Imaging, 12–14 June 2014, Amsterdam, Netherlands, P-0084.

• B. Özkul, B. Kalaycıoğlu, Ö. Özkul, A. Akça, N. İnan. Amyand’s Hernia. European Congress of Radiology, 4–8 Mar 2015, Vienna, Austria, C-2132.

• A. Yazici, O. Özdemir Işık, D. Temiz Karadağ, O. Özkul, C. Albayrak Yasar. A Comparison Between Ankylosing Spondylitis Patients and Familial Mediterranean Fever with Ankylosing Spondylitis Patients. Annual European Congress of Rheumatology, 10–14 June 2015, Rome, Italy, THU-0562.

Book Chapters – National/International Publications

• Özkul Ö. Adjuvant Systemic Therapy Approaches in Gastric Cancer. In: Mertsoylu H, Sedef AM, Aytaç HÖ, Güler OC, eds. Gastrointestinal System Tumors-1. Ankara: Akademisyen Kitabevi; 2019:28. ISBN: 978-605-258-551-1

• Özkul Ö. Locoregional Treatments in Hepatocellular Carcinoma. In: Köse F, Sedef AM, eds. Current Treatment Approaches in Oncology 2. Ankara: Akademisyen Kitabevi; 2019:10. ISBN: 978-605-258-373-9

Poster Presentations

• Çekiç D, Gökosmanoğlu F, Özkul Ö, Varım C, Bayoğlu İV, Hacıbekiroğlu İ, Eş Zamanlı Pankreas Adenokanseri ve İnsülinoma Olgusu, Abstract Book, 592, P-564, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017,  Antalya, Türkiye
• Çekiç D, Özkul Ö, Şenocak D, Varım C, Bayoğlu İV, Hacıbekiroğlu İ, Tamoksifen Tedavisi Altında Gebelik Saptanan Metastatik Meme Kanseri Olgusu, Abstract Book, 362,  P-108, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017,  Antalya, Türkiye
• İşsever K, Varım C, Özkul Ö, Hacıbekiroğlu İ, Bayoğlu İV, Bilir C, Altınbaş M, Larinks, Mesane ve Mide Metakron Kanser: Olgu Sunumu, Abstract Book, 530, P-433, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017, Antalya, Türkiye
• İşsever K, Varım C, Özkul Ö, Hacıbekiroğlu İ, Bayoğlu İV, Bilir C, Altınbaş M, Supraklaviküler Lenf Bezi Metastazı Yapan Rektum Kanseri Olgusu, Abstract Book, 479, P-328, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017,  Antalya, Türkiye
• Yıldırım B, Özkul B, Anık Y, Özkul Ö, kça A, Demirci A, MALTomanın bilateral parotis ve lakrimal gland tutulumu. 34. Ulusal Radyoloji Kongresi, 6-10 Kasım 2013, Antalya, PS-0569. 
• Şenocak D, Özkul Ö, Çekiç D, Varım C, Bayoğlu İV, Hacıbekiroğlu İ, Multipl Primer Tümör; Olgu Sunumu, Abstract Book, 528, P-428, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017, Antalya , Türkiye
• Özkul Ö, Özkul B, Hacıbekiroğlu İ, “Multipl Primer Tümörlü Olgu Sunumu”, Abstract Book, 526, P-423, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017, Antalya, Türkiye
• Özkul Ö,  Özkul B, Hacıbekiroğlu İ, Bayoğlu İV, “Renal Hücreli Karsinom ve Kardiak Metastazı”, Abstract Book, 548, P-472, 22. Ulusal Kanser Kongresi, 19-23 Nisan 2017, Antalya, Türkiye
• Özkul B, Özkul Ö, Agresif Menenjiom. Türk Nöroradyoloji Derneği 27. Yıllık Toplantısı, 16-18 Şubat 2018, İstanbul, P23.
• Özkul B, Özkul Ö,  Bilir C, Hacıbekiroğlu İ, Metastatik Renal Hücreli Kanserde Sitokin Tedavisi Sonrası Endobronşial Fungus Topu Gelişmesi, Gençlerle Onkolojiye Bakış Kongresi, 15-18 Şubat 2018, Antalya, P11.
• Özkul Ö, Özkul B, Bilir C, Hacıbekiroğlu İ, Tarlov Kisti ve Metastatik Meme Tümörü, Gençlerle Onkolojiye Bakış Kongresi, 15-18 Şubat 2018, Antalya, P10.
• Özkul Ö, Hacıbekiroğlu İ, Özkul B, Merkel Hücreli Karsinoma ile Testiküler Karsinoma Birlikteliği Bulunan Olgu, Gençlerle Onkolojiye Bakış Kongresi, 15-18 Şubat 2018, Antalya, P9.
• Özkul Ö, Bilir C, Hacıbekiroğlu İ, Kızılkaya B, Kanser Hastalarında Sistatin C Düzeyleri ile Sağkalım Arasındaki İlişki, Gençlerle Onkolojiye Bakış Kongresi, 15-18 Şubat 2018, Antalya, Türkiye, P6.
• Özkul Ö, Bilir C, Bayoğlu İV, Meme Kanseri ve Ca 19-9 Yüksekliği, Gençlerle Onkolojiye Bakış Kongresi, 15-18 Şubat 2018, Antalya, Türkiye, P36.
• Özkul Ö, Bilir C, Kızılkaya B, Hacıbekiroğlu İ, Terminal Dönem Kanser Hastalarında Enflamatuar Belirteçlerin Önemi, Gençlerle Onkolojiye Bakış Kongresi, 15-18 Şubat 2018, Antalya, Türkiye, P7.

Citations

• Work: A study on basic demographic and disease characteristics of cancer-diagnosed Syrian refugees treated in the border city of Turkey, Sanliurfa; a hospital-based retrospective case series study

1. Hikmat A-R, Faris T, Nayef A-R, Maryam E-A, Baha’ S, Rawan M, Razan M, Rayan B. Late presentation and suboptimal treatment of breast cancer among Syrian refugees: a retrospective study. J Int Med Res. 2021 May;49(5). doi: 10.1177/03000605211018448

2. Tezer K, Mehmet K, İrem Ö, İbrahim B, Meral K, Sinem A, Fahad A, Yavuz K, Hüseyin T, Mustafa D, Richard S. Cancer among Syrian refugees living in Konya Province, Turkey. Confl Health. 2022;16:3. https://dx.doi.org/10.1186/s13031-022-00434-

3. Shailja S, Mariella M, Michelle FG, Mahdis K, Reena PJ, Daina A, Sarah M, Amruta R, Fahad JS, Anushka A, Zulfigar AB. Delivering non-communicable disease interventions to women and children in conflict settings: a systematic review. BMJ Glob Health. 2020;5(Suppl 1): e002047. doi: 10.1136/bmjgh-2019-002047

• Work: Regorafenib or rechallenge chemotherapy: which is more effective in the third-line treatment of metastatic colorectal cancer?

4. Tejaswini PR, Usman K, Ethan AB, Maen A. Chemotherapy rechallenge in metastatic colon cancer: A case report and literature review. World J Clin Oncol. 2020 Nov 24;11(11):959-967. doi: 10.5306/wjco.v11.i11.959

• Work: Efficacy of regorafenib in the second- and third-line setting for patients with advanced hepatocellular carcinoma: A real-life multicenter study from Turkey

5. Jingjun H, Yongjian G, Wensou H, Xiaotao H, Yi Q, Liteng L, Jingwen Z, Licong L, Yaqin Z, Juan Z, Mingyue C, Kangshun Z. J Hepatocell Carcinoma. 2022 Mar;10:157-170. doi: 10.2147/JHC.S353956

6. Mustafa K, Yagmur A, Gunes O, Serif S, Zeynep FK, Esra E. Changes in Wnt and TGF-β signaling mediate the development of regorafenib resistance in hepatocellular carcinoma cell line HuH7. Front Cell Dev Biol. 2021 Aug 11;9:639779. doi: 10.3389/fcell.2021.639779

• Work: Are there any differences among psoriasis, psoriatic arthritis, and rheumatoid arthritis in terms of metabolic syndrome and cardiovascular risk factors?

7. George EF, Gerasimos E, Nikolaos T, Kalliopi F, Stylianos P, George K, Alexios I, Katerina C, Petros PS, Maria GT. Higher depression rates and similar cardiovascular comorbidity in psoriatic arthritis compared with rheumatoid arthritis and diabetes mellitus. Ther Adv Musculoskelet Dis. 2020 Dec 8;12:1759720X20976975. doi: 10.1177/1759720X20976975

8. Beatrice AC, Cristina DP, Andreea LB, Sineta CF, Ştefan CD, Roxana MD, Raluca ES, Paulina LC, Florentin AV. Facing the Unseen – Metabolic Syndrome in Psoriatic Arthritis. Curr Health Sci J. 2020 Jul-Sep;46(3):280-284. doi: 10.12865/CHSJ.46.03.09