Doç. Dr.Mehmet Gökçü

  • İlgi Alanları
  • Servikal lezyonlar
  • Rahim kanseri
  • Yumurtalık kanseri
  • Rahim ağzı kanseri
  • Endometriozis tedavisi
  • Pelvik ağrı tedavisi
  • Laparoskopik cerrahi
  • Kolposkopi

(HİPEC) Sıcak kemoterapi olarak da bilinen hipertermik intraperitoneal kemoterapi ileri evre peritona yayılmış over (yumurtalık) kanserlerinde, karın boşluğunun ısıtılmış kemoterapi ilaçlarıyla doldurularak yıkanmasını içeren bir kanser tedavi yöntemidir.  Ameliyat esnasında karın bölgesindeki tümörlerin tamamen çıkarılmasını takiben, hastanın karın boşluğuna 40-42 santigrat sıcaklık aralığındaki kemoterapötik ilaç 60-90 dakika süresince uygulanır.

Kullanılan kemoterapötik ilaç seçimi tümörün en duyarlı olduğu ilaç gurubu ile yapılır. İlaç miktarı hastanın vücut yüzeyine göre ayarlanarak, özel bir perfüzyon pompası ile 42 santigrat dereceye kadar ısıtılır ve karın içi boşluğunda bütün dokulara nüfus edecek şekilde uygulanır. Bu işlem yaklaşık 90 sürer ve bu esnada batın içindeki tüm dokular bu kemoterapötik madde ile yıkanır.

Hipertermi iki şekilde etkisini gösterir. İlk olarak tümöral hücre proteinlerinin yıkılması ile hücre ölümü gerçekleştirir, ikinci olarak da ısı etkisi ile kemoterapötik ajanların dokulara daha derin etki etmesini sağlar.

Bu esnada süren perfüzyon ile de karın içindeki serbest dolaşan tümör hücreleri yıkama etkisi ile temizlenirler.

Eğitim ve Uzmanlık
2011 - Tıpta Uzmanlık Kurulu Jinekolojik Onkoloji Cerrahisi
2001 - Ankara Etlik Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum
1996 - Hacettepe Üniversitesi İng. Tıp Fakültesi

Deneyim
2001 - 2005 Ankara Etlik Eğitim ve Araştırma Hastanesi/ Uzman hekim
2005 - 2020 Tepecik Eğitin Araştırma Hastanesi/ Uzman hekim
2012- Jinekolojik Onkoloji Cerrahisi Yandal Uzmanlığı
2018 - Kadın Hastalıkları Doçentliği
2019 - 2021 T.C. Sağlık Bilimleri Üniversitesi Tepecik Eğitim ve
Araştırma Hastanesi Jinekolojik Onkoloji Klinik Şefi
2021 - İzmir Ekonomi Üniversitesi Medikal Park Hastanesi

Kurs ve Sertifikalar
Robotik Cerrahi sertifikası
İleri Düzey Laparoskopi sertifikası

Mesleki Üyelikler
European Society of Gynaecological Oncology
Minimal İnvaziv Jinekolojik Onkoloji Derneği
Servikal Patolojiler ve Kolposkopi Derneği
Türk Obstetrik ve Jinekoloji Derneği
Türk Jinekolojik Onkoloji Derneği
Robotik Jinekolojik Cerrahi Derneği
Türk Tabipler Birliği
Pelvik Ağrı ve Endometriozis Derneği

Ödüller
2010 - Diploma De Honra Republica Da Guina Bissau
2012 - İnsanlığa Hizmet Beratı World Wide Doctors

Uluslararası hakemli dergilerde yayımlanan makaleler


1. M. Gökçü, , K. Güngördük,  V. Gülseven , M. Kocaer,  O. Gungorduk , M. Sancı.. 

Comparison of four different treatment modalities in Stage IIA cervical cancer: single center experience of 22 years.  Eur. J. Gynaecol. Oncol. –ISSN, : 0392-2936.XXXVIX, n. 1, 2018

 

2. Gokcu M, Gungorduk K, Aşıcıoğlu O, Çetinkaya N, Güngör T, Pakay G, Cüylan ZF, Toptaş T, Özyurt R, Ağaçayak E, Ozdemir A, Erol O, Turan A, Gülseren V, İcen MS, Şenol T, Güraslan H, Yücesoy B, Sahbaz A, Gungorduk O, Besimoğlu B, Pakay K, Temizkan O, Sancı M, Şimşek T, Meydanlı MM, Harma M, Yaşar L, Boran B, Uysal AD, Karateke A.

 Borderline ovarian tumors: clinical characteristics, management, and outcomes - a multicenter study. J Ovarian Res. 2016 Oct 18;9(1):66. PubMed PMID: 27756415; PubMed Central PMCID: PMC5070357.

 

 

3. Ayhan A, Toptas T, Oz M, Vardar MA, Kayikcioglu F, Ozgul N, Gokcu M, Simsek T, Tunc M, Meydanli MM. Low-grade endometrial stromal sarcoma: A Turkish uterine sarcoma group study analyzing prognostic factors and disease outcomes. Gynecol Oncol. 2021 Mar;160(3):674-680. doi: 10.1016/j.ygyno.2020.12.017. Epub 2020 Dec 27. PMID: 33375988.          04-Mar-2021

 

4. Cuylan ZF, Akilli H, Gungorduk K, Demirkiran F, Oz M, Salman MC, Sozen H, Celik H, Gokcu M, Bese T, Meydanli MM, Ozgul N, Topuz S, Kuscu E, Kuru O, Gokmen S, Gultekin M, Ayhan A. Is the extent of lymphadenectomy a prognostic factor in International Federation of Gynecology and Obstetrics stage II endometrioid endometrial cancer? J Obstet Gynaecol Res. 2021 Mar;47(3):1134-1144. doi: 10.1111/jog.14648. Epub 2021 Jan 10. PMID: 33426779.  01-Mar-2021

 

5. Ayhan A, Tunc M, Boran N, Khatib G, Gokcu M, Simsek T, Ozen OI, Toptas T, Yalcin I, Meydanli MM. High-grade endometrial stromal sarcoma versus undifferentiated uterine sarcoma: a Turkish uterine sarcoma group study-001. Arch Gynecol Obstet. 2021 Jan 3. doi: 10.1007/s00404-020-05915-6. Epub ahead of print. PMID: 33392719.  03-Jan-2021

 

6. Güngördük K, Plett H, Gülseren V, Meydanlı M, Boyraz G, Özdemir İ, Şahin H, Şenol T, Yıldırım N, Turan T, Öge T, Gökçü M, Taşkın S, Ayhan A, Ataseven B. Is the Oncological Outcome of Early Stage Uterine Carcinosarcoma Different from That of Grade 3 Endometrioid Adenocarcinoma? Oncol Res Treat. 2021;44(1-2):43-51. doi: 10.1159/000511288. Epub 2020 Nov 27. PMID: 33249415.          27-Nov-2020

 

7. Karataşlı V, Çakır İ, Can B, Erkılınç S, Karadeniz T, Kuru O, Gökçü M, Sancı M. Does ovarian preservation have an effect on recurrence of early stage low-grade endometrial stromal sarcoma? J Obstet Gynaecol. 2020 Oct 16:1-6. doi: 10.1080/01443615.2020.1803238. Epub ahead of print. PMID: 33063586.         16-Oct-2020 

 

8. Selvi Demirtas G, Gokcu M, Sancı M, Ekmekci S, Yıldız HI. Primary non-Hodgkin's lymphoma masquerading as cervical cancer. Ginekol Pol. 2020;91(9):571. doi: 10.5603/GP.2020.0090. PMID: 33030739. 01-Oct-2020 

 

9. Akgor U, Kuru O, Sakinci M, Boyraz G, Sen S, Cakır I, Turan T, Gokcu M, Gultekin M, Sayhan S, Salman C, Ozgul N. Neuroendocrine carcinoma of the endometrium: A very rare gynecologic malignancy. J Gynecol Obstet Hum Reprod. 2020 Aug 19:101897. doi: 10.1016/j.jogoh.2020.101897. Epub ahead of print. PMID: 32827837.   19-Aug-2020           

 

10. Gülseren V, Çakır İ, Özdemir İA, Sancı M, Gökçü M, Güngördük K. The role of changes in systemic inflammatory response markers during neoadjuvant chemotherapy in predicting suboptimal surgery in ovarian cancer. Curr Probl Cancer. 2020 Aug;44(4):100536. doi: 10.1016/j.currproblcancer.2020.100536. Epub 2020 Jan 15. PMID: 31980146.           12-Aug-2020       

 

11. Aslan K, Meydanli MM, Akilli H, Durmuş Y, Gökçü M, Kayıkçıoğlu F, Demirkiran F, Ayhan A. Does lymph node ratio have any prognostic significance in maximally cytoreduced node-positive low-grade serous ovarian carcinoma? Arch Gynecol Obstet. 2020 Jul;302(1):183-190. doi: 10.1007/s00404-020-05580-9. Epub 2020 May 14. PMID: 32409929.    01-Jul-2020 

 

12. Karataşlı V, Erkılınç S, Çakır İ, Can B, Karadeniz T, Gökçü M, Sancı M. The effect of lymph node metastasis on overall survival and disease-free survival in vulvar cancer patients. Ginekol Pol. 2020;91(2):62-67. doi: 10.5603/GP.2020.0018. PMID: 32141050.    17-Jun-2020

 

13. Karataşlı V, Can B, Çakır İ, Erkılınç S, Karabulut A, Ayaz D, Kuru O, Gökçü M, Sancı M. Effect of tumor size on the accuracy of frozen section in the evaluation of mucinous borderline ovarian tumors. J Gynecol Obstet Hum Reprod. 2020 Jun;49(6):101765. doi: 10.1016/j.jogoh.2020.101765. Epub 2020 Apr 20. PMID: 32325272.       01-Jun-2020

 

14. Erkılınç S, Taylan E, Karataşlı V, Uzaldı İ, Karadeniz T, Gökçü M, Sancı M. Does lymphadenectomy effect postoperative surgical morbidity and survival in patients with adult granulosa cell tumor of ovary? J Obstet Gynaecol Res. 2019 May;45(5):1019-1025. doi: 10.1111/jog.13928. Epub 2019 Feb 13. PMID: 30761709. 07-May-2020           

 

15. Güngördük K, Aşıcıoğlu O, Gülseren V, Özdemir İA, Kocaer M, Çakır İ, Gökçü M, Sancı M. Evaluation of the optimal laparoscopic method for benign ovarian mass extraction: a transumbilical route using a bag made from a surgical glove versus a lateral transabdominal route employing a standard endobag. J Obstet Gynaecol. 2020 Apr;40(3):378-381. doi: 10.1080/01443615.2019.1623765. Epub 2019 Oct 4. PMID: 31584305. 01-Apr-2020

 

16. Karataşlı V, Erkılınç S, Can B, Çakır İ, Temel O, Gökçü M, Sancı M. Cervical carcinosarcoma presented in advanced stage after high grade cervical displasia. J Exp Ther Oncol. 2019 Dec;13(2):165-167. PMID: 31881134. 10-Dec-2019

 

17. Gulseren V, Kocaer M, Gungorduk O, Ozdemir IA, Gokcu M, Mart EM, Sanci M, Gungorduk K. Preoperative predictors of pelvic and para-aortic lymph node metastases in cervical cancer. J Cancer Res Ther. 2019 Oct-Dec;15(6):1231-1234. doi: 10.4103/jcrt.JCRT_467_17. PMID: 31898653. 01-Dec-2019

 

18. Erkilinç S, Karataşli V, Demir B, Çakir İ, Can B, Karadeniz T, Gökçü M, Sanci M. Rectosigmoidectomy and Douglas Peritonectomy in the Management of Serosal Implants in Advanced-Stage Ovarian Cancer Surgery: Survival and Surgical Outcomes. Int J Gynecol Cancer. 2018 Nov;28(9):1699-1705. doi: 10.1097/IGC.0000000000001368. PMID: 30371561.        18-Dec-2018

 

19. Gülseren V, Kocaer M, Güngördük Ö, Özdemir İA, Gölbaşı C, Budak A, Çakır İ, Gökçü M, Sancı M, Güngördük K. Stage IB1 cervical cancer treated with modified radical or radical hysterectomy: does size determine risk factors? Ginekol Pol. 2018;89(12):667-671. doi: 10.5603/GP.a2018.0112. PMID: 30618033.  01-Dec-2018

 

20.Gülseren V, Kocaer M, Güngördük Ö, Özdemir İA, Gölbaşı C, Budak A, Gökçü M, Sancı M, Güngördük K. Isolated pulmonary metastases in patients with cervical cancer and the factors affecting survival after recurrence. Ginekol Pol. 2018;89(11):593-598. doi: 10.5603/GP.a2018.0102. PMID: 30508210.  08-Nov-2018

 

21. Aşıcıoğlu O, Gungorduk K, Ozdemir A, Güngördük Ö, Gokçü M, Yaşar L, Sancı M. A novel preoperative scoring system based on 18-FDG PET-CT for predicting lymph node metastases in patients with high-risk endometrial cancer. J Obstet Gynaecol. 2019 Jan;39(1):105-109. doi: 10.1080/01443615.2018.1467884. Epub 2018 Sep 6. PMID: 30187784.           01-Sep-2018

 

22. Kahraman DS, Diniz G, Sayhan S, Sayar C, Ayaz D, Gokcu M, Karadeniz T. The prognostic significance of pdl1 and foxp3 expressions in tumor cells and the tumor microenvironment of ovarian epithelial tumors. Int J Clin Exp Pathol. 2018 Aug 1;11(8):3884-3890. PMID: 31949776; PMCID: PMC6962806.   01-Aug-2018           

 

23. Erkilinç S, Taylan E, Gülseren V, Erkilinç G, Karadeniz T, Bağci M, Temel O, Solmaz U, Gökçü M, Sanci M. The Effect of Adenomyosis in Myometrial Invasion and Overall Survival in Endometrial Cancer. Int J Gynecol Cancer. 2018 Jan;28(1):145-151. doi: 10.1097/IGC.0000000000001137. PMID: 29040186.          09-Jan-2018

 

24. Güngördük K, Güngördük ÖC, Ozdemir IA, Gokcu M, Sanci M. Does BLOODCARE Powder Prevent Postoperative Chylous Ascites After Lymphadenectomy for Gynecological Malignancies? Int J Gynecol Cancer. 2017 Nov;27(9):1979-1982. doi: 10.1097/IGC.0000000000001093. PMID: 28763366.          14-Nov-2017

 

25. Kebapcı E, Gülseren V, Tuğmen C, Gökçü M, Solmaz U, Sert İ, Kocaer M, Özer M, Ölmez M, Sancı M. Outcomes of patients with advanced stage ovarian cancer with intestinal metastasis. Ginekol Pol. 2017;88(10):537-542. doi: 10.5603/GP.a2017.0098. PMID: 29192414.   01-Nov-2017

 

26. Biler A, Solmaz U, Erkilinc S, Gokcu M, Bagci M, Temel O, Karadeniz T, Sanci M. Analysis of endometrial carcinoma in young women at a high-volume cancer center. Int J Surg. 2017 Aug;44:185-190. doi: 10.1016/j.ijsu.2017.06.083. Epub 2017 Jun 30. PMID: 28673864.        14-Aug-2017 

 

27. Güngördük K, Özdemir İA, Güngördük Ö, Gülseren V, Gokçü M, Sancı M. Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: a randomized controlled trial. Am J Obstet Gynecol. 2017 Feb;216(2):145.e1-145.e7. doi: 10.1016/j.ajog.2016.10.019. Epub 2016 Oct 22. PMID: 27780709.           08-Feb-2017

 

28. Güngördük K, Kocaer M, Gülseren V, Özdemir AI, Gokcu M, Güngördük O, Sancı M. Management of Isolated Vaginal Metastasis in Squamous Cell Cervical Cancer: 23 Years' Experience at a Single Center. Oncol Res Treat. 2016;39(10):616-621. doi: 10.1159/000448540. Epub 2016 Sep 10. PMID: 27710973. 07-Dec-2016

 

29. Alanyali S, Duran Ö, Özsaran Z, Özsaran A, Akman L, Solmaz U, Gökçü M, Sanci M, Aras AB. Treatment results and prognostic factors of patients with vulvar cancer treated with postoperative or definitive radiotherapy. Tumori. 2016 Jun 2;2016(3):311-5. doi: 10.5301/tj.5000509. Epub 2016 Apr 14. PMID: 27079905. 02-Jun-2016

 

30. Ozcan A, Mumusoglu S, Gokcu M, Caypinar SS, Sagiroglu C, Inan AH, Aktoz F, Biler A, Turan V, Töz E, Ozdemir IA, Bozdag G. Differentiated therapy in pre- and postmenopausal adnexal torsion based on malignancy rates: A retrospective multicentre study over five years. Int J Surg. 2016 May;29:95-100. doi: 10.1016/j.ijsu.2016.03.042. Epub 2016 Mar 19. PMID: 27004419. 02-Mar-2016

 

31. Akman L, Ertas IE, Gokcu M, Terek MC, Sanci M, Sanli UA, Zekioglu O, Ozsaran AA. Ovarian sertoli-leydig cell tumors: A multicenter long-term clinicopathological analysis of 27 patients. J Cancer Res Ther. 2016 Jan-Mar;12(1):290-4. doi: 10.4103/0973-1482.158037. PMID: 27072253.        01-Jan-2016

 

32. Gungorduk K, Sahbaz A, Ozdemir A, Gokcu M, Sancı M, Köse MF. Management of cervical cancer during pregnancy. J Obstet Gynaecol. 2016;36(3):366-71. doi: 10.3109/01443615.2015.1065235. Epub 2015 Oct 14. PMID: 26467977.          01-Jan-2016

 

33. Sayhan S, Diniz G, Karadeniz T, Ayaz D, Kahraman DS, Gokcu M, Yildirim HT. Expression of caveolin-1 in peritumoral stroma is associated with histological grade in ovarian serous tumors. Ginekol Pol. 2015 Jun;86(6):424-8. doi: 10.17772/gp/2398. PMID: 26255449. 01-Dec-2015

 

34. Adiyeke M, Sanci M, Karaca I, Gökçü M, Töz E, Ocal E. Surgical management of intrauterine devices migrated towards intra-abdominal structures: 20-year experience of a tertiary center. Clin Exp Obstet Gynecol. 2015;42(3):358-60. PMID: 26152011.           01-Nov-2015

 

35. Gungorduk K, Ertas IE, Ozdemir A, Akkaya E, Telli E, Taskin S, Gokcu M, Guzel AB, Oge T, Akman L, Toptas T, Solmaz U, Dogan A, Terek MC, Sanci M, Ozsaran A, Simsek T, Vardar MA, Yalcin OT, Ozalp S, Yildirim Y, Ortac F. Prognostic Significance of Retroperitoneal Lymphadenectomy, Preoperative Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio in Primary Fallopian Tube Carcinoma: A Multicenter Study. Cancer Res Treat. 2015 Jul;47(3):480-8. doi: 10.4143/crt.2014.058. Epub 2014 Nov 17. PMID: 2      01-Jul-2015 

 

36. Gungorduk K, Ozdemir A, Ertas IE, Gokcu M, Telli E, Oge T, Sahbaz A, Sayhan S, Sanci M, Harma M, Ozalp S. Adjuvant treatment modalities, prognostic predictors and outcomes of uterine carcinosarcomas. Cancer Res Treat. 2015 Apr;47(2):282-9. doi: 10.4143/crt.2014.009. Epub 2014 Sep 4. PMID: 25358384; PMCID: PMC4398122.     15-Apr-2015

 

37. Solmaz U, Turan V, Mat E, Dereli ML, Ekin A, Peker N, Tosun G, Dogan A, Gokcu M, Sanci M. Chylous ascites following retroperitoneal lymphadenectomy in gynecologic malignancies: incidence, risk factors and management. Int J Surg. 2015 Apr;16(Pt A):88-93. doi: 10.1016/j.ijsu.2015.02.020. Epub 2015 Mar 9. PMID: 25765351.  08-Apr-2015

 

38. Gungorduk K, Ozdemir A, Ertas IE, Sahbaz A, Asicioglu O, Gokcu M, Solmaz U, Harma M, Uzuncakmak C, Dogan A, Sanci M. A novel preoperative scoring system for predicting endometrial cancer in patients with complex atypical endometrial hyperplasia and accuracy of frozen section pathological examination in this context: a multicenter study. Gynecol Obstet Invest. 2015;79(1):50-6. doi: 10.1159/000365086. Epub 2014 Sep 18. PMID: 25247588.      11-Feb-2015  

 

39. Gungorduk K, Ozdemir A, Ertas IE, Selcuk I, Solmaz U, Ozgu E, Mat E, Gokcu M, Karadeniz T, Akbay S, Sanci M, Meydanli MM, Ayaz D, Gungor T. Is mucinous adenocarcinoma of the endometrium a risk factor for lymph node involvement? A multicenter case-control study. Int J Clin Oncol. 2015 Aug;20(4):782-9. doi: 10.1007/s10147-014-0767-2. Epub 2014 Nov 8. PMID: 25380693. 05-Jan-2015

 

40. Gungorduk K, Ozdemir A, Gökçü M, Sancı M. Does lubrication of the vaginal speculum reduce pain during a gynecologic oncology examination? Eur J Obstet Gynecol Reprod Biol. 2015 Jan;184:84-8. doi: 10.1016/j.ejogrb.2014.11.006. Epub 2014 Nov 20. PMID: 25481363.        01-Jan-2015

 

41. Ozdemir A, Gungorduk K, Ulker K, Yasar L, Ertas IE, Gokcu M, Solmaz U, Sanci M. Umbilical stalk elevation technique for safer Veress needle insertion in obese patients: a case-control study. Eur J Obstet Gynecol Reprod Biol. 2014 Sep;180:168-71. doi: 10.1016/j.ejogrb.2014.06.012. Epub 2014 Jun 23. PMID: 25027266.      11-Sep-2014

 

42. Hanhan HM, Gungorduk K, Ozdemir İA, Gokcu M, Sanci M, Ayaz D, Özeren M. Primary retroperitoneal mucinous cystadenocarcinoma during pregnancy. J Obstet Gynaecol. 2014 Aug;34(6):535-8. doi: 10.3109/01443615.2014.910501. Epub 2014 May 15. PMID: 24832037.        13-Aug-2014           

 

43. Gungorduk K, Ertas IE, Sahbaz A, Ozvural S, Sarica Y, Ozdemir A, Sayhan S, Gokcu M, Yilmaz B, Sanci M, Inan S, Harma M, Yildirim Y. Immunolocalization of ERK1/2 and p-AKT in normal endometrium, endometrial hyperplasia, and early and advanced stage endometrioid endometrial adenocancer and their prognostic significance in malignant group. Eur J Obstet Gynecol Reprod Biol. 2014 Aug;179:147-52. doi: 10.1016/j.ejogrb.2014.05.040. Epub 2014 Jun 5. PMID: 24965996. 01-Aug-2014           

 

44. Ozalp SS, Telli E, Oge T, Tulunay G, Boran N, Turan T, Yenen M, Kurdoglu Z, Ozler A, Yuce K, Ulker V, Arvas M, Demirkiran F, Bese T, Tokgozoglu N, Onan A, Sanci M, Gokcu M, Tosun G, Dikmen Y, Ozsaran A, Terek MC, Akman L, Yetimalar H, Kilic DS, Gungor T, Ozgu E, Yildiz Y, Kokcu A, Kefeli M, Kuruoglu S, Yuksel H, Guvenal T, Hasdemir PS, Ozcelik B, Serin S, Dolanbay M, Arioz DT, Tuncer N, Bozkaya H, Guven S, Kulaksiz D, Varol F, Yanik A, Ogurlu G, Simsek T, Toptas T, Dogan S, Camuzoglu H, Api M, G      04-Jun-2014

 

45. Ertas IE, Gungorduk K, Ozdemir A, Emirdar V, Gokcu M, Dogan A, Solmaz U, Yildirim Y. Pelvic tuberculosis, echinococcosis, and actinomycosis: great imitators of ovarian cancer. Aust N Z J Obstet Gynaecol. 2014 Apr;54(2):166-71. doi: 10.1111/ajo.12191. Epub 2014 Feb 8. PMID: 24506530. 09-Apr-2014

 

46.Arslanpence I, Dede FS, Gokcu M, Gelisen O. Impetigo herpetiformis unresponsive to therapy in a pregnant adolescent. J Pediatr Adolesc Gynecol. 2003 Jun;16(3):129-32. doi: 10.1016/s1083-3188(03)00040-8. PMID: 12804935.           11-Jun-2003